Protein Alignment IGF2BP1 and Igf2bp1

DIOPT Version :10

• Sequence 1: NP_006537.3
• Gene: IGF2BP1 / 10642
• HGNCID: 28866
• Length: 577
• Species: Homo sapiens
• Sequence 2: NP_783184.1
• Gene: Igf2bp1 / 303477
• RGDID: 708580
• Length: 577
• Species: Rattus norvegicus
• Alignment Length: 577
• Identity: 575/577 - (99%)
• Similarity: 576/577 - (99%)
• Gaps: 0/577 - (0%)

Human     1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGKVELQG 65
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat     1 MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDCPDEHWAMKAIETFSGKVELQG 65

Human    66 KRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETAVVNVTYSNRE 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 KRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLAQYGTVENCEQVNTESETAVVNVTYSNRE 130

Human   131 QTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVD 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 QTRQAIMKLNGHQLENHALKVSYIPDEQIAQGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQQVD 195

Human   196 IPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMI 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 IPLRLLVPTQYVGAIIGKEGATIRNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMI 260

Human   261 LEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPER 325
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 LEIMHKEAKDTKTADEVPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPER 325

Human   326 TITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSV 390
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 TITVKGAIENCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSV 390

Human   391 TGAAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVI 455
            ||||||.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||:
  Rat   391 TGAAPYGSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSKVRMVV 455

Human   456 ITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAE 520
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   456 ITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGKTVNELQNLTAAE 520

Human   521 VVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 577
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   521 VVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQKGQSNQAQARRK 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IGF2BP1	NP_006537.3	RRM1_IGF2BP1	1..77	CDD:241069	75/75 (100%)
		RRM2_IGF2BP1	81..156	CDD:410037	74/74 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	160..190		29/29 (100%)
		KH-I_IGF2BP1_rpt1	197..272	CDD:411918	74/74 (100%)
		KH-I_IGF2BP1_rpt2	273..369	CDD:411921	95/95 (100%)
		Sufficient for nuclear export	310..324		13/13 (100%)
		KH-I_IGF2BP1_rpt3	404..479	CDD:411924	73/74 (99%)
		Sufficient for nuclear export	485..495		9/9 (100%)
		KH-I_IGF2BP1_rpt4	487..562	CDD:411927	74/74 (100%)
Igf2bp1	NP_783184.1	RRM1_IGF2BP1	1..77	CDD:241069	75/75 (100%)
		RRM2_IGF2BP1	81..156	CDD:410037	74/74 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	160..190		29/29 (100%)
		KH-I_IGF2BP1_rpt1	197..272	CDD:411918	74/74 (100%)
		KH-I_IGF2BP1_rpt2	273..369	CDD:411921	95/95 (100%)
		Sufficient for nuclear export. /evidence=ECO:0000250	312..323		10/10 (100%)
		KH-I_IGF2BP1_rpt3	404..479	CDD:411924	73/74 (99%)
		Sufficient for nuclear export. /evidence=ECO:0000250	485..495		9/9 (100%)
		KH-I_IGF2BP1_rpt4	487..562	CDD:411927	74/74 (100%)