Protein Alignment LEFTY1 and scw

DIOPT Version :9

• Sequence 1: NP_066277.1
• Gene: LEFTY1 / 10637
• HGNCID: 6552
• Length: 366
• Species: Homo sapiens
• Sequence 2: NP_001286088.1
• Gene: scw / 46000
• FlyBaseID: FBgn0005590
• Length: 400
• Species: Drosophila melanogaster
• Alignment Length: 296
• Identity: 65/296 - (21%)
• Similarity: 104/296 - (35%)
• Gaps: 85/296 - (28%)

Human   107 LPPNSELVQAVLRLFQEPVPKAALHRHGRLSPRSARARVTVEWLRV---RDDGSNRTSLIDSRLV 168
            :|.:..||||:||::::|            |....||..||...|.   |.|.|.|  ::.|...
  Fly   140 VPVDLSLVQAMLRIYKQP------------SLVDRRANFTVSVYRKLDNRQDFSYR--ILGSVNT 190

Human   169 SVHESGWKAFDVTEAVNFWQQLSRPRQPLLLQVSVQREHLGPLASGAHKLVRFASQGAPAGLGEP 233
            :..:.||..|::|:.:.:|          |....:||.:...::.|..:|..||     |||..|
  Fly   191 TSSQRGWLEFNLTDTLRYW----------LHNKGLQRRNELRISIGDSQLSTFA-----AGLVTP 240

Human   234 QLELHTL------------------------DLGDYGAQGDCDPEAP------MTEGTRCCRQEM 268
            |....:|                        ||....|.|...|..|      ......|.|...
  Fly   241 QASRTSLEPFIVGYFNGPELLVKIQKLRFKRDLEKRRAGGGSPPPPPPPPVDLYRPPQSCERLNF 305

Human   269 YIDLQGMKWAENWVLEPPGFLAYECVGTCRQP-------------PEALAFKWPFLGPRQCIASE 320
            .:|.:.:. ..|||:.|..|.||.|.|.|..|             ...:..|.|.|....|:.:.
  Fly   306 TVDFKELH-MHNWVIAPKKFEAYFCGGGCNFPLGTKMNATNHAIVQTLMHLKQPHLPKPCCVPTV 369

Human   321 TDSLPMIVSIKEGGRTRPQVVSLPNMR---VQKCSC 353
            ..::.::..:.|      .::.|...:   .::|.|
  Fly   370 LGAITILRYLNE------DIIDLTKYQKAVAKECGC 399

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
LEFTY1	NP_066277.1	TGFb_propeptide	<106..214	CDD:307025	27/109 (25%)
		TGF_beta	263..353	CDD:306518	21/105 (20%)
scw	NP_001286088.1	TGFb_propeptide	39..254	CDD:279078	37/142 (26%)
		TGFB	300..400	CDD:214556	22/107 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3900
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810