Protein Alignment RGS14 and rgs14a

DIOPT Version :10

• Sequence 1: XP_047272594.1
• Gene: RGS14 / 10636
• HGNCID: 9996
• Length: 619
• Species: Homo sapiens
• Sequence 2: XP_009305919.4
• Gene: rgs14a / 327368
• ZFINID: ZDB-GENE-030131-5579
• Length: 554
• Species: Danio rerio
• Alignment Length: 599
• Identity: 231/599 - (38%)
• Similarity: 312/599 - (52%)
• Gaps: 97/599 - (16%)

Human     1 MPGKPKHLGVPNGRMVLAVSDGELSSTTGPQGQGEGRGSSLSIHSLPSGPSSPFPTEEQPVASWA 65
            |..|...|.||.|.|..|||||||:......|.    .||||..|..||.|.........|.|||
Zfish    46 MSKKMSSLAVPTGLMTQAVSDGELNLRLSSCGS----SSSLSESSSRSGGSQAADGPASRVVSWA 106

Human    66 LSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQA 130
            :.||.||:|.:|:.||||||:.|.||||:.|::|||:|::||.|..:::.:|||.||..|||..:
Zfish   107 VCFEHLLEDHVGVRYFTEFLRSEVSAENILFYQACEKFKKIPTSRLEEMKKEARLIYDTFLSESS 171

Human   131 LSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAEGRPLRE 195
            |..||||..|...|..|..|.||||...|.|||.|||.|||.|||:||||:.|:||..|.|||
Zfish   172 LHAVNIDDTAQTEERELEMPTPDMFNKAQAQIFKLMKMDSYTRFVRSPLYQNCMLACVESRPL-- 234

Human   196 PGSSRLGSPDATRKVRGTGRGTGRGRGSCGPRARGDASGCRSASLCPRSACGLGPSPVPAPPLYP 260
               ..:|:|:                    |:::          :..:||         .||...
Zfish   235 ---PSIGTPE--------------------PKSK----------MSKKSA---------TPPSNR 257

Human   261 QKPKLKPGKSLPLGVEELGQLPPVEGPGGRPLRKSFRRELGGTANAALRRESQGSLNSSASLDLG 325
            :..:||    :|....:..:...:|..|.....:||.|      .|..|:|||.|:.|::||:
Zfish   258 KSVELK----VPSSDSKTSRKKRLENRGSWGADQSFER------MAVSRKESQISVKSNSSLE-- 310

Human   326 FLAFVSSKSESHRKSLGSTEGE--SESRP--GKYCCVYLPDGTASLALARPGLTIRDMLAGICEK 386
             |...|.::|:.|.|:..::.|  |...|  .||||||||||||||..||.||::|||::.:|||
Zfish   311 -LVSGSGRAENGRCSVAVSDPEALSSGSPTADKYCCVYLPDGTASLVSARAGLSLRDMISSLCEK 374

Human   387 RGLSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLENRITFELELTALERVVRISAKPTKRLQE 451
            |...|.|:.:||.|.: |.|.|||||::..||::.||.:|||.||:..|.|.:.|.||.:|.:.|
Zfish   375 RAFPLRDVLLYLRGKD-KPLSLDQDCSMFGDQQLSLELKITFALEIAFLGRTIGIIAKSSKSVGE 438

Human   452 ALQPILEKHGLSPLEVVLHRPGEKQPLDLGKLVSSVAAQRLVLDTLPGVKISKARDKSPCRSQGC 516
            ||..:|||..|.|.:|.|...|....|::...|..:|.:.:.||. ..::|..:...:...|:|
Zfish   439 ALSSVLEKQQLRPQDVQLSLSGSNDALNMSTSVFRLANKTVRLDR-AALEIQTSSPSARANSRG- 501

Human   517 PPRTQDKATHPPPASPSSLVKVPSSATGKRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLP 581
                                         |:..|::||||||||.|.|.|.||||||.||.|.:|
Zfish   502 -----------------------------RKHQDVDGLVELLNRAQCSRADDQRGLLTKEQLEIP 537

Human   582 EFLQLPAQGPSSEE 595
            :||||||.|...:|
Zfish   538 QFLQLPAGGAEDQE 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RGS14	XP_047272594.1	RGS_RGS14	58..186	CDD:188697	68/127 (54%)
		RBD1_RGS14	354..424	CDD:340657	40/69 (58%)
		RBD2_RGS14	425..496	CDD:340659	26/70 (37%)
		GoLoco	552..573	CDD:460481	15/20 (75%)
rgs14a	XP_009305919.4	None