Protein Alignment GAS2L1 and pigs

DIOPT Version :10

• Sequence 1: NP_006469.2
• Gene: GAS2L1 / 10634
• HGNCID: 16955
• Length: 681
• Species: Homo sapiens
• Sequence 2: NP_572331.2
• Gene: pigs / 31596
• FlyBaseID: FBgn0029881
• Length: 977
• Species: Drosophila melanogaster
• Alignment Length: 829
• Identity: 257/829 - (31%)
• Similarity: 349/829 - (42%)
• Gaps: 223/829 - (26%)

Human    13 AKSVRPFRSSEAYVEAMKEDLAEWLNALYGLGLPGGGDGFLTGLATGTTLCQHANAVTEAARALA 77
            |:..|||:|||.|:|||:|||||||:.||. .|....|.|:..|.||..||:|||.|.:||....
  Fly     6 ARPYRPFKSSEEYLEAMREDLAEWLSTLYP-ELSINADNFMDRLDTGVALCKHANYVRQAAVDYL 69

Human    78 AARPAR-------------------GVAFQAHSVVPGSFMARDNVATFIGWCRVELGVPEVLMFE 123
            |.|.||                   |......:...|:|.|||||:.||.|||..|.:.|.|:||
  Fly    70 ARRQARNKSMTRSMTSGLAGPILAMGNVHYLPAAKSGTFFARDNVSNFITWCRKSLKIIECLLFE 134

Human   124 TEDLVLRKNEKSVVLCLLEVARRGARLGLLAPRLVQFEQEIERELRAAPPAPNAPAAGEDTTET- 187
            |:||::|||||.|:|||||||||||:.|:|||.|||.|::|:||: ||....|.....|:.|:|
  Fly   135 TDDLIMRKNEKHVILCLLEVARRGAKFGMLAPMLVQMERQIDREI-AADIKANGAGCSENGTQTD 198

Human   188 APAPGTPARG--------------------------------------PRMTPSDLRNLDELVRE 214
            |...|..:..                                      |::..:||::|||:||:
  Fly   199 ALETGNSSAATMTTITTTTVETDLYDDSDDSETEDDGDQNPVLMYGPQPQIITNDLKSLDEMVRD 263

Human   215 ILGRCTCPDQFPMIKVSEGKYRVGDSSLLIFVRVLRSHVMVRVGGGWDTLEHYLDKHDPCRCSST 279
            ::.:||||.||||::|||||||:||:.:|||||:||||||||||||||||.|||||||||||.:
  Fly   264 LVEKCTCPSQFPMVRVSEGKYRIGDTKVLIFVRILRSHVMVRVGGGWDTLSHYLDKHDPCRCRA- 327

Human   280 AHRPPQPRVCTFSPQRVSPTTSPRPASPVPGSERRGSRP--EMTPVSLR------STKEGPET-- 334
            .||       :....|:.|..||. .:|..|.|...::.  |.:|.:.|      :...||.|
  Fly   328 QHR-------SSVAARLIPRQSPN-HNPSNGIELHKAQVIFERSPPAARRVFNSPNCNGGPGTGS 384

Human   335 -----------PPRPRDQLPPHPRSRRYSGDS------------DSSASSAQSGPLGTRSDDTGT 376
                       ||..::.....|.|.:|...|            :....::.:|...|.:.||.:
  Fly   385 SCGTGVVGVAVPPTLQNGHSLSPNSGKYRSRSPTPQRKFLNQQANGGGIASATGSSQTVTTDTSS 449

Human   377 GPRRERPSRRLTTGTPASPRRPPALRSQ--SRDRLDRGRPRGAP----------GGRGAQLSVPS 429
            |.....||....:.:| ||||...:|.:  |.|....| |:..|          ||.|    |.|
  Fly   450 GQLLGSPSLARRSMSP-SPRRLIDMRKKQSSLDSYSSG-PKSLPGYSCSMEEANGGSG----VGS 508

Human   430 PARRARSQSREEQAVLLVRRDRDGQHSWVPRGRGSGGSGRSTPQTPRARSPAAPRLSRVSSPSPE 494
            .|....|                          ||.|||.:..|      ..|.:...:|....|
  Fly   509 AAGGVSS--------------------------GSAGSGVAGEQ------GGANKFENISDNGSE 541

Human   495 LGTTPASIFRT--PLQLDPQQEQQLFRRLE-EEFLANARALEAVASVTPTGPAPDPARAP----- 551
            :....   :|:  .:|...|:.:.|..:.. |:..:||| |:..:|.:...|:.:||...
  Fly   542 ISDEG---YRSLGVIQSGAQKRESLHSQASIEDAESNAR-LDQTSSDSQISPSDEPAEKATTDIL 602

Human   552 ----------DPPAPDSAYCSSSSS----SSSLSVLGGKCGQPG----------DSGRT-----A 587
                      :....|.:.|....|    .|....|..|..|.|          |..:|     |
  Fly   603 EEEDLNGQDREEDQEDYSVCDGPQSLPAILSGAHKLSDKFEQSGVFITDDEITVDIAKTEDQSVA 667

Human   588 N--GLPGPRSQALSSS--------SDEGSPCPGMGGPLD-------APGSPLACTEPSRTWARGR 635
            |  |.|.|....:..|        |.:.|.|.|.||.|.       .|....:..:|.....|.|
  Fly   668 NTMGNPTPNLSKIPRSPLAQRRRRSIDNSTCGGAGGSLQDLSSRSGLPAPAFSRKQPVYRSVRTR 732

Human   636 MDTQPDRKPSRIPTPRGPRRPSGPAEL-------GTWHALHSVTPRAEP 677
            ..|      ....||..|.|.....:|       .||....:..|:..|
  Fly   733 NST------GATTTPVAPPRSRQATQLPMVRDVTNTWSGRTTGAPKRRP 775

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GAS2L1	NP_006469.2	CH_GAS2L1_2	18..152	CDD:409117	74/152 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	168..204		9/74 (12%)
		GAS2	208..276	CDD:460480	52/67 (78%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	278..509		56/277 (20%)
		PHA03247	<283..662	CDD:223021	98/477 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	536..681		41/200 (21%)
pigs	NP_572331.2	CH_GAS2L1_2	11..163	CDD:409117	74/152 (49%)
		GAS2	257..325	CDD:460480	52/67 (78%)