Protein Alignment TRIM16 and Trim16

DIOPT Version :10

• Sequence 1: NP_006461.3
• Gene: TRIM16 / 10626
• HGNCID: 17241
• Length: 564
• Species: Homo sapiens
• Sequence 2: NP_444399.2
• Gene: Trim16 / 94092
• MGIID: 2137356
• Length: 556
• Species: Mus musculus
• Alignment Length: 565
• Identity: 438/565 - (77%)
• Similarity: 482/565 - (85%)
• Gaps: 10/565 - (1%)

Human     1 MAELDLMAPGPLPRATAQPPAPLSPDSGSPSPDSGSASPVEEEDVGSSEKLGRETEEQDSDSAEQ 65
            ||||||:|||||...||.|.|||       .||..||.|.|:||.....|.|.||:||..|.||.
Mouse     1 MAELDLIAPGPLTGVTAHPLAPL-------GPDPVSAIPAEKEDADPLSKSGEETQEQGHDPAEV 58

Human    66 GDPAGEGKEVLCDFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRY 130
            |.| ||..::|||||| ...||:|||||||||||||||||:|||.|.||.||.||||.||.:.|.
Mouse    59 GAP-GEEDQILCDFCL-GASRVRAVKSCLTCMVNYCEEHLRPHQENSKLHSHQLTEPAKDQDLRT 121

Human   131 CPAHHSPLSAFCCPDQQCICQDCCQ-EHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAI 194
            ||||||||.:||...||||||:|.: ||.|.:.||||||||:||.:|:|.|||||:|||||||||
Mouse   122 CPAHHSPLVSFCHTHQQCICQECGEGEHRGDSTVSLDAARRNKEVDLRCMQLDLEQKLKLNENAI 186

Human   195 SRLQANQKSVLVSVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRS 259
            :|||||.|||||||||||.|||.:|||||||||||||:||:||||||||||:|.|.||.|||:||
Mouse   187 ARLQANHKSVLVSVSEVKVVAEEKFGELLAAVRKAQADVMVFLEEKEQAALNQVNSIKTHLEHRS 251

Human   260 AEMEKSKQELERMAAISNTVQFLEEYCKFKNTEDITFPSVYVGLKDKLSGIRKVITESTVHLIQL 324
            .|||||||||||:|||||||.|||||||.|.|||...||:|:||||||||||||||:||::||||
Mouse   252 LEMEKSKQELERLAAISNTVLFLEEYCKLKKTEDTASPSIYIGLKDKLSGIRKVITDSTLNLIQL 316

Human   325 LENYKKKLQEFSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQ 389
            ||:||:||||||:||||||||||||:|||||.||||||.||::|||||.||||||||||:|||||
Mouse   317 LESYKEKLQEFSREEEYDIRTQVSAIVQRKYRTSKPEPRTRDEFLQYACDITFDPDTAHRYLRLQ 381

Human   390 EENRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGE 454
            |:|||||||||||||||||||||||||||||||||||||||||||:.|.||||||||||||||||
Mouse   382 EDNRKVTNTTPWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVELSGGGTYVGLTCKGIDRKGE 446

Human   455 ERNSCISGNNFSWSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLV 519
            |||||||||:||||:.|||||||||:||.|||||..||||||:|::||||||||||||||.|||:
Mouse   447 ERNSCISGNSFSWSIHWNGKEFTAWHSDTETPLKVSPFRRLGIYVNFPGGILSFYGVEYDAMTLI 511

Human   520 HKFACKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAPSLVGTAP 564
            |||.|||||||||||||||||||||||||||||||||.|.|..||
Mouse   512 HKFDCKFSEPVYAAFWLSKKENAIRIVDLGEEPEKPAGSSVEAAP 556

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIM16	NP_006461.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..69		35/67 (52%)
		Bbox1_TRIM16	75..122	CDD:380897	35/46 (76%)
		Bbox_SF	129..173	CDD:469587	29/44 (66%)
		CusB_dom_1	<164..>283	CDD:481212	97/118 (82%)
		SPRY_PRY_TRIM16	365..546	CDD:293948	159/180 (88%)
Trim16	NP_444399.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..60		34/65 (52%)
		Bbox1_TRIM16	67..113	CDD:380897	35/46 (76%)
		SCP-1	<108..>362	CDD:114219	195/253 (77%)
		Bbox2_TRIM16-like	120..165	CDD:380827	29/44 (66%)
		SPRY_PRY_TRIM16	357..538	CDD:293948	159/180 (88%)