Protein Alignment TRIM16 and trim16

DIOPT Version :10

• Sequence 1: NP_006461.3
• Gene: TRIM16 / 10626
• HGNCID: 17241
• Length: 564
• Species: Homo sapiens
• Sequence 2: NP_001315091.1
• Gene: trim16 / 568734
• ZFINID: ZDB-GENE-090512-6
• Length: 589
• Species: Danio rerio
• Alignment Length: 550
• Identity: 244/550 - (44%)
• Similarity: 344/550 - (62%)
• Gaps: 27/550 - (4%)

Human    27 SGSPSPDSGSASPVEEEDVGSSE--------------KLGRETEEQDSDSAEQGDPAGEGKEVLC 77
            :||| |:..:..   |:||.:.|              |..::.::.|.|..|:.:.......|.|
Zfish    43 NGSP-PEKHTEG---EKDVKTIEESKIQKDLKEIEVNKESKDPQKDDEDDEEEEEEVLGPDVVTC 103

Human    78 DFCLDDTRRVKAVKSCLTCMVNYCEEHLQPHQVNIKLQSHLLTEPVKDHNWRYCPAHHSPLSAFC 142
            |.|:|...|.|  ||||||:|:|||.||:||..|.|.|||.|.:|::|...|.|.||.|||..:|
Zfish   104 DSCIDKPCRAK--KSCLTCLVSYCESHLRPHLENAKFQSHRLVDPLRDIERRTCEAHRSPLELYC 166

Human   143 CPDQQCICQDC-CQEHSGHTIVSLDAARRDKEAELQCTQLDLERKLKLNENAISRLQANQKSVLV 206
            |  ..|:|..| .:||.||..:.:..|||:.|.|||..|.::.:.:...||||::||.|..|:..
Zfish   167 C--MCCLCPACVTEEHLGHQALPIAEARRNIEKELQDKQTEMLKTMTAAENAINKLQVNTVSIEG 229

Human   207 SVSEVKAVAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRSAEMEKSKQELER 271
            ||.||:||.|.||..|.|||.:.:.:|...||.:|:.||.||:||:.|||.|.||::|::..:::
Zfish   230 SVQEVRAVMEEQFSILQAAVEQVKRDVCELLEAEERQALRQADGIRVHLEQRCAELKKTQSRVQK 294

Human   272 MAAISNTVQFLEEYCKF-KNTEDITFPSVYVGLKDKLSGIRKVITESTVHLI-QLLENYKKKLQE 334
            ::...:.:.||:||.:: |...|::.|.||:||.|:|.....||..||..:. .|..:|..||::
Zfish   295 ISKNKHDIHFLQEYSEWKKEAVDVSLPGVYIGLVDRLQAFSHVIVRSTNRMCDNLHSSYTNKLKD 359

Human   335 FSKEEEYDIRTQVSAVVQRKYWTSKPEPSTREQFLQYAYDITFDPDTAHKYLRLQEENRKVTNTT 399
            ..|.:...|:|.|.||:..|.....|:|.||:.||||...::.|.:|||.:|||.||.:||||||
Zfish   360 TCKNDNVGIKTTVFAVMAAKKNMMLPDPKTRDDFLQYVTPLSLDANTAHVFLRLTEECKKVTNTT 424

Human   400 PWEHPYPDLPSRFLHWRQVLSQQSLYLHRYYFEVEIFGAGTYVGLTCKGIDRKGEERNSCISGNN 464
            ||:|.|||||.||..::|||:|:|.||.|:||||::.|.||:||||.|.|||||.:.||||:|||
Zfish   425 PWQHSYPDLPERFQDFKQVLTQESFYLGRHYFEVDMKGEGTHVGLTYKSIDRKGSQSNSCIAGNN 489

Human   465 FSWSLQWNGKEFTAWYSDMETPLKAGPFRRLGVYIDFPGGILSFYGVEYDTMTLVHKFACKFSEP 529
            |||.|||||:.|:||:||:||||.......:|:|:|:.||:|:||.|| :.|||:||:..:|.||
Zfish   490 FSWCLQWNGRSFSAWHSDVETPLSCPKTTHIGIYVDYSGGLLAFYDVE-NGMTLIHKYQAEFLEP 553

Human   530 VYAAFWLSKKENAIRIVDLGEEP-EKPAPS 558
            :|.||||.||||.:.:......| ..|:||
Zfish   554 LYPAFWLPKKENVVLLEPGAASPLSSPSPS 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIM16	NP_006461.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..69		12/55 (22%)
		Bbox1_TRIM16	75..122	CDD:380897	27/46 (59%)
		Bbox_SF	129..173	CDD:469587	19/44 (43%)
		CusB_dom_1	<164..>283	CDD:481212	47/118 (40%)
		SPRY_PRY_TRIM16	365..546	CDD:293948	106/180 (59%)
trim16	NP_001315091.1	Bbox_SF	101..146	CDD:469587	27/46 (59%)
		COG4372	194..>295	CDD:443500	43/100 (43%)
		SPRY_PRY_TRIM16	390..569	CDD:293948	106/179 (59%)