Protein Alignment TRIM16 and ntc

DIOPT Version :10

• Sequence 1: NP_006461.3
• Gene: TRIM16 / 10626
• HGNCID: 17241
• Length: 564
• Species: Homo sapiens
• Sequence 2: NP_647829.1
• Gene: ntc / 38443
• FlyBaseID: FBgn0035461
• Length: 314
• Species: Drosophila melanogaster
• Alignment Length: 285
• Identity: 56/285 - (19%)
• Similarity: 101/285 - (35%)
• Gaps: 84/285 - (29%)

Human   198 QANQKSVLVSVSEVKA---VAEMQFGELLAAVRKAQANVMLFLEEKEQAALSQANGIKAHLEYRS 259
            |.|::.| |...::||   |.:.|...|:.. :..|....|.||.             |.||:..
  Fly    29 QQNEQQV-VGTKDIKAPDQVGKKQRPRLIQE-KSTQETNPLILEH-------------ATLEWVP 78

Human   260 AEMEK---SKQELERMAA-----ISNTVQFLEEYCKFKNTEDI--------------TFPSVYVG 302
            ..|:|   ..||..:|.|     :...:..||  |.|...|..              :|.:..|.
  Fly    79 QHMDKLLNQYQECRKMPAAEWLHLLTYLVALE--CGFVEEETFAQKRHLIQPVPSFSSFHAQNVR 141

Human   303 LKDKLSGIRKVITESTVHLIQLLENYKKKLQEFSKEEEYDIRTQVSAVVQRKYW----------T 357
            :..:.....:|....||::::|    :..|.:.:.||     |.:.|.:|.:..          |
  Fly   142 ILSEQPARYEVCFNDTVYIMRL----RTLLDKHAPEE-----TSLVAALQCRLMAVSLGDQLMIT 197

Human   358 SKPEPSTREQFLQYAYDITF------------DPDTAHKYLRLQEENRKVTNTTPWEHPYPDLPS 410
            ..|.|.::|.    .|.::.            :....|::.:|.|.:.::.     :|.:..:.|
  Fly   198 LSPAPPSKEP----GYSVSLSIGRYVLNIQAKNKPIYHRFRKLDELSYQLK-----QHLFQPMRS 253

Human   411 RFLHWRQVLSQQSL--YLHRYYFEV 433
            :.|...::..|.||  .....|||:
  Fly   254 QQLMQMEMKLQPSLLGLPDELYFEI 278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIM16	NP_006461.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..69
		Bbox1_TRIM16	75..122	CDD:380897
		Bbox_SF	129..173	CDD:469587
		CusB_dom_1	<164..>283	CDD:481212	22/95 (23%)
		SPRY_PRY_TRIM16	365..546	CDD:293948	14/83 (17%)
ntc	NP_647829.1	F-box-like	267..>298	CDD:463757	4/12 (33%)