Protein Alignment POLR3G and Polr3G

DIOPT Version :10

• Sequence 1: NP_006458.2
• Gene: POLR3G / 10622
• HGNCID: 30075
• Length: 223
• Species: Homo sapiens
• Sequence 2: NP_788522.1
• Gene: Polr3G / 39941
• FlyBaseID: FBgn0053051
• Length: 211
• Species: Drosophila melanogaster
• Alignment Length: 226
• Identity: 66/226 - (29%)
• Similarity: 111/226 - (49%)
• Gaps: 25/226 - (11%)

Human     1 MAGNKGRGRAAYTFNIEAVGFSKGEKLPDVVLKPPPLFPDTDYKPVPLKTGEGEEYMLALKQELR 65
            ||| :|||....|...|.:......|...|...|||.||....:|..|:|...:.|.|..|::..
  Fly     1 MAG-RGRGGKTGTLTAEQMAMLGCTKDMPVQTAPPPTFPPVLNRPTTLETTATQNYQLLWKEDFL 64

Human    66 ETMKRMPYF-IETPEERQDIER--YSKRYMKVYKEEWIPD--WRRLPREM-MPRNKCKKAGPKPK 124
            ..|:..||: |....:.::::.  :.::.|:..|....||  ::.:|:|: :...|.:.|..:|.
  Fly    65 NRMRDSPYYMISASRDAKNLDHKDWREKAMERMKLTAQPDFNYKAMPQELNISSRKRRGADARPN 129

Human   125 KAKDAGKGTPLTNTEDVLKKMEELEKRGDGEKSDEENEEKEGSKEKSKEGDDDDDDDAAEQEEYD 189
            ..      |..||.||.||.:|:.|.:..|.:.||..:|.:..:|      :::|.:||..:|.|
  Fly   130 LL------TKKTNIEDRLKVLEQKELKSGGGEQDENKQESDSEQE------EEEDPEAALDDEMD 182

Human   190 EEEQEEENDYINSYFEDGDDFGADSDDNMDE 220
                 |:|||..:||::|:.|. |.|||:|:
  Fly   183 -----EDNDYGATYFDNGEAFN-DEDDNLDD 207

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POLR3G	NP_006458.2	RNA_pol_3_Rpc31	33..173	CDD:463324	38/145 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	110..223		35/112 (31%)
Polr3G	NP_788522.1	RNA_pol_3_Rpc31	29..196	CDD:463324	50/183 (27%)