Protein Alignment TRIM3 and Trim3

DIOPT Version :10

• Sequence 1: XP_047282213.1
• Gene: TRIM3 / 10612
• HGNCID: 10064
• Length: 827
• Species: Homo sapiens
• Sequence 2: XP_038948510.1
• Gene: Trim3 / 83616
• RGDID: 70074
• Length: 750
• Species: Rattus norvegicus
• Alignment Length: 750
• Identity: 735/750 - (98%)
• Similarity: 739/750 - (98%)
• Gaps: 6/750 - (0%)

Human    84 MAKREDSPGPEVQPMDKQFLVCSICLDRYQCPKVLPCLHTFCERCLQNYIPAQSLTLSCPVCRQT 148
            |||||||||||||||||||||||||||||:|||||||||||||||||||||.|||||||||||||
  Rat     1 MAKREDSPGPEVQPMDKQFLVCSICLDRYRCPKVLPCLHTFCERCLQNYIPPQSLTLSCPVCRQT 65

Human   149 SILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSVVAGRPLSCPNHEGK------TME 207
            |||||||||||||||||||||||||||||||||||||||||.||||||||||||||      |||
  Rat    66 SILPEQGVSALQNNFFISSLMEAMQQAPDGAHDPEDPHPLSAVAGRPLSCPNHEGKEPLYHQTME 130

Human   208 FYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQ 272
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   131 FYCEACETAMCGECRAGEHREHGTVLLRDVVEQHKAALQRQLEAVRGRLPQLSAAIALVGGISQQ 195

Human   273 LQERKAEALAQISAAFEDLEQALQQRKQALVSDLETICGAKQKVLQSQLDTLRQGQEHIGSSCSF 337
            |||||||||||||||||||||||||||||||||||:||||||||||:||||||||||||||||||
  Rat   196 LQERKAEALAQISAAFEDLEQALQQRKQALVSDLESICGAKQKVLQTQLDTLRQGQEHIGSSCSF 260

Human   338 AEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTS 402
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   261 AEQALRLGSAPEVLLVRKHMRERLAALAAQAFPERPHENAQLELVLEVDGLRRSVLNLGALLTTS 325

Human   403 ATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELRAEITGPDGTRLPVPVVDHKNG 467
            |||||||||||||||||||||||||||||||||||||||||||.||||||||.||.|||||||||
  Rat   326 ATAHETVATGEGLRQALVGQPASLTVTTKDKDGRLVRTGSAELCAEITGPDGVRLAVPVVDHKNG 390

Human   468 TYELVYTARTEGELLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKA 532
            ||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   391 TYELVYTARTEGDLLLSVLLYGQPVRGSPFRVRALRPGDLPPSPDDVKRRVKSPGGPGSHVRQKA 455

Human   533 VRRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFS 597
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   456 VRRPSSMYSTGGKRKDNPIEDELVFRVGSRGREKGEFTNLQGVSAASSGRIVVADSNNQCIQVFS 520

Human   598 NEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPK 662
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   521 NEGQFKFRFGVRGRSPGQLQRPTGVAVDTNGDIIVADYDNRWVSIFSPEGKFKTKIGAGRLMGPK 585

Human   663 GVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNH 727
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   586 GVAVDRNGHIIVVDNKSCCVFTFQPNGKLVGRFGGRGATDRHFAGPHFVAVNNKNEIVVTDFHNH 650

Human   728 SVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTS 792
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   651 SVKVYSADGEFLFKFGSHGEGNGQFNAPTGVAVDSNGNIIVADWGNSRIQVFDSSGSFLSYINTS 715

Human   793 AEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ 827
            |||||||||||||||||||||||||||||||||||
  Rat   716 AEPLYGPQGLALTSDGHVVVADAGNHCFKAYRYLQ 750

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TRIM3	XP_047282213.1	RING-HC_TRIM3	99..146	CDD:438424	44/46 (96%)
		Bbox2_TRIM3_C-VII	190..236	CDD:380883	44/51 (86%)
		BBC	241..367	CDD:128778	123/125 (98%)
		IG_FLMN	405..502	CDD:214720	92/96 (96%)
		NHL_TRIM2_like	554..827	CDD:271330	272/272 (100%)
		NHL repeat	572..611	CDD:271330	38/38 (100%)
		NHL repeat	619..658	CDD:271330	38/38 (100%)
		NHL repeat	661..698	CDD:271330	36/36 (100%)
		NHL repeat	705..746	CDD:271330	40/40 (100%)
		NHL repeat	752..794	CDD:271330	41/41 (100%)
		NHL repeat	797..823	CDD:271330	25/25 (100%)
Trim3	XP_038948510.1	RING-HC_TRIM3	16..63	CDD:438424	44/46 (96%)
		Bbox_SF	107..159	CDD:469587	44/51 (86%)
		BBC	164..290	CDD:128778	123/125 (98%)
		IG_FLMN	328..425	CDD:214720	92/96 (96%)
		NHL_TRIM2_like	477..750	CDD:271330	272/272 (100%)
		NHL repeat	495..534	CDD:271330	38/38 (100%)
		NHL repeat	542..581	CDD:271330	38/38 (100%)
		NHL repeat	584..621	CDD:271330	36/36 (100%)
		NHL repeat	628..669	CDD:271330	40/40 (100%)
		NHL repeat	675..717	CDD:271330	41/41 (100%)
		NHL repeat	720..746	CDD:271330	25/25 (100%)