DRSC/TRiP Functional Genomics Resources

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Protein Alignment MXD4 and Max

DIOPT Version :9

Sequence 1:NP_006445.1 Gene:MXD4 / 10608 HGNCID:13906 Length:209 Species:Homo sapiens
Sequence 2:NP_001246833.1 Gene:Max / 40095 FlyBaseID:FBgn0017578 Length:161 Species:Drosophila melanogaster


Alignment Length:163 Identity:37/163 - (22%)
Similarity:66/163 - (40%) Gaps:40/163 - (24%)


- Green bases have known domain annotations that are detailed below.


Human    34 DGDF-----AREKTKAAGLVRKAPNNRSSHNELEKHRRAKLRLYLEQLKQLVPL--GPDSTRHTT 91
            |||.     :...|..|...:  ...|:.||.||:.||..::.....|::.||.  |..::|   
  Fly    17 DGDSDTGLGSSRHTNTANFTQ--AEKRAHHNALERRRRDHIKESFTNLREAVPTLKGEKASR--- 76

Human    92 LSLLKRAKVHIKKLEEQDRRALSIK----EQLQQEHRFLKRRLEQLSVQSVERVRTDSTGSAVST 152
            ..:||:....|:.:    ||.:|..    |::::::..:.::::.|.         .|.|...|.
  Fly    77 AQILKKTTECIQTM----RRKISENQKDIEEIKRQNNIIAKQIQALE---------SSNGDQFSE 128

Human   153 DDSEQEVDIEGMEFGPGELDSVGSSSDADDHYS 185
            ..|::||       |..|.|    ..|.|..:|
  Fly   129 FLSDEEV-------GSEEAD----DEDLDQDFS 150

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MXD4NP_006445.1 Interaction with SIN3A and SIN3B. /evidence=ECO:0000250 6..23
bHLHzip_Mad4 53..140 CDD:381499 20/92 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 140..209 12/46 (26%)
MaxNP_001246833.1 HLH 40..91 CDD:278439 15/57 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2483
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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