Protein Alignment POMT1 and Pomt1

DIOPT Version :10

• Sequence 1: NP_009102.4
• Gene: POMT1 / 10585
• HGNCID: 9202
• Length: 747
• Species: Homo sapiens
• Sequence 2: NP_001411588.1
• Gene: Pomt1 / 99011
• MGIID: 2138994
• Length: 748
• Species: Mus musculus
• Alignment Length: 746
• Identity: 623/746 - (83%)
• Similarity: 681/746 - (91%)
• Gaps: 22/746 - (2%)

Human     1 MWGFLKRPVVVTADINLSLVALTGMGLLSRLWRLTYPRAVVFDEVYYGQYISFYMKQIFFLDDSG 65
            |..|||||:|||.||||:||||||:|||:|||:|:|||||||||||||||||||||:||||||||
Mouse    25 MLRFLKRPLVVTVDINLNLVALTGLGLLTRLWQLSYPRAVVFDEVYYGQYISFYMKRIFFLDDSG 89

Human    66 PPFGHMVLALGGYLGGFDGNFLWNRIGAEYSSNVPVWSLRLLPALAGALSVPMAYQIVLELHFSH 130
            ||||||:|||||:||||||||||||||||||||||:|||||||||||||||||||||||||||||
Mouse    90 PPFGHMLLALGGWLGGFDGNFLWNRIGAEYSSNVPIWSLRLLPALAGALSVPMAYQIVLELHFSH 154

Human   131 CAAMGAALLMLIENALITQSRLMLLESVLIFFNLLAVLSYLKFFNCQKHSPFSLSWWFWLTLTGV 195
            .||:|||||||||||||||||||||||:|||||||||||||||||.|.|||||:.||.||.||||
Mouse   155 GAAIGAALLMLIENALITQSRLMLLESILIFFNLLAVLSYLKFFNSQTHSPFSVHWWLWLLLTGV 219

Human   196 ACSCAVGIKYMGVFTYVLVLGVAAVHAWHLLGDQTLSNVGADVQCCMRPACMGQMQMSQGVCVFC 260
            :|||||||||||:|||:||||:||||||:|:|||||||        ||              |..
Mouse   220 SCSCAVGIKYMGIFTYLLVLGIAAVHAWNLIGDQTLSN--------MR--------------VLS 262

Human   261 HLLARAVALLVIPVVLYLLFFYVHLILVFRSGPHDQIMSSAFQASLEGGLARITQGQPLEVAFGS 325
            |||||.|||||:||.||||||||||:|::||||||||||||||||||||||||||||||||||||
Mouse   263 HLLARIVALLVVPVFLYLLFFYVHLMLLYRSGPHDQIMSSAFQASLEGGLARITQGQPLEVAFGS 327

Human   326 QVTLRNVFGKPVPCWLHSHQDTYPMIYENGRGSSHQQQVTCYPFKDVNNWWIVKDPRRHQLVVSS 390
            ||||::|.|||:|||||||::|||||||||||||||||||||||||:|||||||||.||||||::
Mouse   328 QVTLKSVSGKPLPCWLHSHKNTYPMIYENGRGSSHQQQVTCYPFKDINNWWIVKDPGRHQLVVNN 392

Human   391 PPRPVRHGDMVQLVHGMTTRSLNTHDVAAPLSPHSQEVSCYIDYNISMPAQNLWRLEIVNRGSDT 455
            |||||||||:||||||||||.|||||||||||||||||||||||||||||||||:|:||||.|:.
Mouse   393 PPRPVRHGDIVQLVHGMTTRLLNTHDVAAPLSPHSQEVSCYIDYNISMPAQNLWKLDIVNRESNR 457

Human   456 DVWKTILSEVRFVHVNTSAVLKLSGAHLPDWGYRQLEIVGEKLSRGYHGSTVWNVEEHRYGASQE 520
            |.|||||||||||||||||:||||||||||||:||||:||||||.|||.|.||||||||||.|.|
Mouse   458 DTWKTILSEVRFVHVNTSAILKLSGAHLPDWGFRQLEVVGEKLSPGYHESMVWNVEEHRYGKSHE 522

Human   521 QRERERELHSPAQVDVSRNLSFMARFSELQWRMLALRSDDSEHKYSSSPLEWVTLDTNIAYWLHP 585
            |:|||.|||||.|:|:|||||||||||||||:||.|:::|.||:|||:||||:||||||||||||
Mouse   523 QKERELELHSPTQLDISRNLSFMARFSELQWKMLTLKNEDLEHQYSSTPLEWLTLDTNIAYWLHP 587

Human   586 RTSAQIHLLGNIVIWVSGSLALAIYALLSLWYLLRRRRNVHDLPQDAWLRWVLAGALCAGGWAVN 650
            |||||||||||||||.|.|||..:|.||..||||||||::.|||:|||.|||||||||.||||:|
Mouse   588 RTSAQIHLLGNIVIWTSASLATVVYTLLFFWYLLRRRRSICDLPEDAWSRWVLAGALCTGGWALN 652

Human   651 YLPFFLMEKTLFLYHYLPALTFQILLLPVVLQHISDHLCRSQLQRSIFSALVVAWYSSACHVSNT 715
            ||||||||:.||||||||||||||||||:||||.|||||||||||::|||||||||||||||||.
Mouse   653 YLPFFLMERVLFLYHYLPALTFQILLLPIVLQHASDHLCRSQLQRNVFSALVVAWYSSACHVSNM 717

Human   716 LRPLTYGDKSLSPHELKALRWKDSWDILIRK 746
            ||||||||.||||.||:||||||||||||||
Mouse   718 LRPLTYGDTSLSPGELRALRWKDSWDILIRK 748

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POMT1	NP_009102.4	PMT	20..289	CDD:396786	217/268 (81%)
		beta-trefoil_MIR_POMT1	321..515	CDD:467752	169/193 (88%)
		PMT_4TMC	544..738	CDD:465056	159/193 (82%)
Pomt1	NP_001411588.1	PMT	56..291	CDD:396786	207/256 (81%)
		beta-trefoil_MIR_POMT1	323..517	CDD:467752	169/193 (88%)
		PMT_4TMC	546..740	CDD:465056	159/193 (82%)