Protein Alignment POMT1 and rt

DIOPT Version :10

• Sequence 1: NP_009102.4
• Gene: POMT1 / 10585
• HGNCID: 9202
• Length: 747
• Species: Homo sapiens
• Sequence 2: NP_524025.2
• Gene: rt / 39297
• FlyBaseID: FBgn0003292
• Length: 886
• Species: Drosophila melanogaster
• Alignment Length: 749
• Identity: 317/749 - (42%)
• Similarity: 465/749 - (62%)
• Gaps: 39/749 - (5%)

Human     7 RPVVVTADINLSLVALTGMGLLSRLWRLTYPRAVVFDEVYYGQYISFYMKQIFFLDDSGPPFGHM 71
            :|..|...|:|....|..:...:|.::|..|..:||||::||:|||.||:.|||.|.. ||.|..
  Fly   165 QPFTVNLRIDLFSWTLFLLAFGTRFYKLATPPHIVFDELHYGKYISMYMRNIFFFDQH-PPLGKQ 228

Human    72 VLALGGYLGGFDGNFLWNRIGAEYSSNVPVWSLRLLPALAGALSVPMAYQIVLELHFSHCAAMGA 136
            ::|....|.|:|||:.:.|||..||..:|::..|.|||:.|:|..|..|.::||...|..::...
  Fly   229 LIAGLVSLAGYDGNYTFTRIGEPYSPEMPIFWFRFLPAMCGSLLAPAVYNLLLEAKLSRWSSALG 293

Human   137 ALLMLIENALITQSRLMLLESVLIFFNLLAVLSYLKFFNCQKHSPFSLSWWFWLTLTGVACSCAV 201
            .||::::|:|:||||.:|:||:|:....:.:...|:|   |:....||.|:|..|...|....|.
  Fly   294 GLLVVLDNSLLTQSRFVLMESMLLLATTVGIACLLRF---QRSRLGSLEWFFTGTAAAVCLGAAG 355

Human   202 GIKYMGVFTYVLVLGVAAVHAWHLLGDQTLSNVGADVQCCMRPACMGQMQMSQGVCVFCHLLARA 266
            .:||:|.....|...:...|.|.||.|..|:    |.|..|                  |.::|.
  Fly   356 TVKYVGFLALGLAFYLLCRHLWQLLYDAGLT----DRQLWM------------------HAISRL 398

Human   267 VALLVIPVVLYLLFFYVHLILVFRSGPHDQIMSSAFQASLEGGLARITQGQPLEVAFGSQVTLRN 331
            :..:.||:.:||..||:|...:.|:||||.||:|||||||:||||.||:||||.|..|||:|||:
  Fly   399 LIFVGIPLAVYLGVFYIHFKTLHRAGPHDSIMTSAFQASLDGGLASITKGQPLAVVHGSQITLRH 463

Human   332 VFGKPVPCWLHSHQDTYPMIYENGRGSSHQQQVTCYPFKDVNNWWIVKDPRRHQLVVSSPPRPVR 396
            ..|:  .||||||...||:.|.:.||||||||||||.||||||||:||.|.:..|||...|..:|
  Fly   464 THGR--TCWLHSHAAVYPVRYPDKRGSSHQQQVTCYSFKDVNNWWLVKRPTKENLVVGDEPDIIR 526

Human   397 HGDMVQLVHGMTTRSLNTHDVAAPLSPHSQEVSCYIDYNISMPAQNLWRLEIVNRGSDTDVWKTI 461
            ||:::|||||:|:|:||:|||||.::|..|||||||||.|.|..:.|||:||:||.|:.|:|..|
  Fly   527 HGEIIQLVHGITSRALNSHDVAAAMTPQCQEVSCYIDYEIKMAGELLWRVEILNRDSEGDIWHAI 591

Human   462 LSEVRFVHVNTSAVLKLSGAHLPDWGYRQLEIVGEKLSRGYHGSTVWNVEEHRYGASQEQRERER 526
            .||||.|||:|.|.||.||..||:||:.|.|:|.:: .:..|...:||||||||..:::.|||||
  Fly   592 KSEVRLVHVSTEASLKFSGRQLPEWGFNQHEVVADR-EKAIHEDAIWNVEEHRYTQTEDHRERER 655

Human   527 ELHSPAQVDVSR-NLSFMARFSELQWRMLALRSDDSEHKYSSSPLEWVTLDTNIAYWLHPRTSAQ 590
            ::.:...:...| .:||.|:..|||.:||........|.|||.|.||..:|..|||||..::|||
  Fly   656 QMLTAEMIPTKRTRISFWAKLLELQSKMLFQTKSVPNHMYSSMPHEWPLMDKGIAYWLDSQSSAQ 720

Human   591 IHLLGNIVIWVSGSLALAIYALLSLWYLLRRRRNVHDLPQDAWLRWVLAGALCAGGWAVNYLPFF 655
            |:|||||::|.:.::.:.:||.|..:|.:||:|...|:.:..|.|:||||.....|:.::|:|:|
  Fly   721 IYLLGNILLWYTATMGILVYAGLLAFYAMRRQRLCFDISEQEWQRFVLAGDTFFMGYVMHYIPYF 785

Human   656 LMEKTLFLYHYLPALTFQILLLPVVLQHISDHLCRS-------QLQRSIFSALVVAWYSSACHVS 713
            .:::||||::||||..|::|||..|::|: |:|.|.       .|.| ::..:::.|......:.
  Fly   786 CVDRTLFLHNYLPAFVFKLLLLCFVVEHL-DYLLRRFCTGRGVHLVR-LYRLMLILWLVGVLSIF 848

Human   714 NTLRPLTYGDKSLSPHELKALRWKDSWDILIRKH 747
            :...|.:||.:.::.:|:::|||||:||.::.|:
  Fly   849 SKFIPFSYGARKMTLNEVRSLRWKDTWDFVLHKN 882

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POMT1	NP_009102.4	PMT	20..289	CDD:396786	89/268 (33%)
		beta-trefoil_MIR_POMT1	321..515	CDD:467752	111/193 (58%)
		PMT_4TMC	544..738	CDD:465056	74/200 (37%)
rt	NP_524025.2	PMT	178..421	CDD:396786	89/268 (33%)
		beta-trefoil_MIR_POMT1	453..644	CDD:467752	111/193 (58%)
		PMT_4TMC	674..873	CDD:465056	74/200 (37%)