Protein Alignment POMT1 and ogm4

DIOPT Version :10

• Sequence 1: NP_009102.4
• Gene: POMT1 / 10585
• HGNCID: 9202
• Length: 747
• Species: Homo sapiens
• Sequence 2: NP_596807.1
• Gene: ogm4 / 2539761
• PomBaseID: SPBC16C6.09
• Length: 778
• Species: Schizosaccharomyces pombe
• Alignment Length: 790
• Identity: 244/790 - (30%)
• Similarity: 387/790 - (48%)
• Gaps: 111/790 - (14%)

Human     6 KRPVVVTADINLSL------------VALTGMGLLSRLWRLTYPRAVVFDEVYYGQYISFYMKQI 58
            |.|.....|::|:|            |.:|.:..::|.|.|..|..||||||::|::.|:|::..
pombe    37 KSPNSTEEDVSLNLKTLKAKKFKLAFVLITVLSFITRFWNLNLPGEVVFDEVHFGKFASYYLQGK 101

Human    59 FFLDDSGPPFGHMVLALGGYLGGFDGNFLWNRIGAEYSSN-VPVWSLRLLPALAGALSVPMAYQI 122
            :|. |..|||..::|||...|.|:||::|::.||..|..| ||..::|..|||..:|..|:.:.|
pombe   102 YFF-DLHPPFAKLLLALVAKLAGYDGHYLFDNIGDNYKDNGVPYVTIRAWPALLSSLVPPVVFLI 165

Human   123 VLELHFSHCAAMGAALLMLIENALITQSRLMLLESVLIFFNLLAVLSYLKFFNCQKHSPFSLSWW 187
            :.|..:...|.:.::.|:|.:||.:|:.||:||::.|:|..:.|:..|::||.. :|:|||..||
pombe   166 MKESGYDLLACIVSSSLVLFDNAHVTEGRLILLDATLLFSMVCAIYCYVRFFKL-RHTPFSRPWW 229

Human   188 FWLTLTGVACSCAVGIKYMGVFTYVLVLGVAAVHAWHLLGDQTLSNVGADVQCCMRPACMGQMQM 252
            .||..||...||.:..||:|.||::.:.....:..|:|...:|
pombe   230 AWLFFTGFFLSCTISTKYVGFFTFLSIGLSVCLELWYLWDIKT---------------------- 272

Human   253 SQGVCV---FCHLLARAVALLVIPVVLYLLFFYVHLILVFRSGPHDQIMSSAFQASLEGGLARIT 314
              |:.|   |.|.|||...|:..|.:.:|.:||:|..::..|||.|..||..||.:|...  .||
pombe   273 --GLTVERFFQHFLARFFCLIFFPFLFFLFWFYMHFNILTISGPGDSFMSLEFQETLSDN--PIT 333

Human   315 QGQPLEVAFGSQVTLRNVFGKPVPCWLHSHQDTYPMIYENGRGSSHQQQVTCYPFKDVNNWWIVK 379
            ....: :.:...||::::   ....:||||.:.||:.|::||.||..||||.|.|.|.||:|::.
pombe   334 ANSTI-LNYYDIVTIKHM---GTNAFLHSHPEKYPIPYDDGRISSGGQQVTGYQFDDENNYWMIL 394

Human   380 DPRRHQLVVSSPP------RPVRHGDMVQLVHGMTTRSLNTHDVAAPLSPHSQEVSCYIDYNISM 438
             |..|.    .||      .||::.|.::|.|..|...|.|||||:|..|.::|.:. :..:.|.
pombe   395 -PADHY----DPPIEAKLNVPVKNMDYIKLHHVGTNTDLMTHDVASPYHPTNEEFTT-VSVDESA 453

Human   439 PAQNLWRLEIVNRGSDTDVWK---TILSEVRFVHVNTSAVLKLSGAHLPDWGYRQLEIVGEKLSR 500
            ..::.:.|..|....:||..:   |..|..:.:|..|...:......||||.::||||.|.|..:
pombe   454 GKKHEYTLFQVVMSDNTDPQRPLYTKASSFKLIHKLTHVAMWSDPKPLPDWAFKQLEINGAKNIQ 518

Human   501 GYHGSTVWNVEEHRYGASQEQRERERELHSPAQVDVSRNLSFMARFSELQWRMLALRSDDSE-HK 564
              .||..|..:: ..|....:.::|::        :.:.|.|..::.|||..|....:..:| |.
pombe   519 --TGSIFWTFDD-IIGLKDSRLKKEKK--------IPKKLPFWKKYLELQLTMFRQNNMLTEFHP 572

Human   565 YSSSPLEWVTLDTNIAYWLHPRTSAQIHLLGNIVIW--VSGS-LALAIYALLSLWYLLRRRRNVH 626
            |||:|.:|.||...||:|.....:.||:||||.:.|  ::|: |:..:.|...   :|.|:|.:.
pombe   573 YSSNPSDWFTLHHGIAFWAKSEENKQIYLLGNPIGWWIIAGTVLSTTVVAAAE---ILLRQRGIR 634

Human   627 DLPQDAWLRWVLAGALCAGGWAVNYLPFFLMEKTLFLYHYLPALTFQILLLPVVLQHISDHLCRS 691
            .||:.....:..:.......:..:|||||:|.:.|||:|||||.....||:...:|    ..||.
pombe   635 TLPETVRNHFYRSTMFFYMTYVFHYLPFFIMGRQLFLHHYLPAHLAGSLLVGAFIQ----LACRK 695

Human   692 QLQRSIFSAL-----VVAWYSSACH---------VSNTL------------RPLTYGDKSLSPHE 730
            ..:..:.:.:     |.....|.||         :...|            .|:||||||||..|
pombe   696 SFRSPVSAGVPIPKDVDEKGHSKCHRKYGHVIELICTLLLIFVVIYCFTFFAPMTYGDKSLSVDE 760

Human   731 LKALRWKDSW 740
            ....:|.|||
pombe   761 WTRRKWLDSW 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
POMT1	NP_009102.4	PMT	20..289	CDD:396786	91/272 (33%)
		beta-trefoil_MIR_POMT1	321..515	CDD:467752	64/202 (32%)
		PMT_4TMC	544..738	CDD:465056	66/223 (30%)
ogm4	NP_596807.1	PMT	63..310	CDD:396786	91/272 (33%)
		beta-trefoil_MIR_PMT4-like	339..529	CDD:467756	64/201 (32%)
		PMT_4TMC	551..768	CDD:465056	66/223 (30%)