Protein Alignment NPC2 and NPC2

DIOPT Version :10

• Sequence 1: NP_001350617.1
• Gene: NPC2 / 10577
• HGNCID: 14537
• Length: 174
• Species: Homo sapiens
• Sequence 2: NP_010237.1
• Gene: NPC2 / 851514
• SGDID: S000002204
• Length: 173
• Species: Saccharomyces cerevisiae
• Alignment Length: 171
• Identity: 41/171 - (23%)
• Similarity: 66/171 - (38%)
• Gaps: 46/171 - (26%)

Human     4 LAATFLLLALSTAA---------------QAEPVQ----FKDCGSVDG---VIKEVNVSPCPTQP 46
            |.|.|.||.|.|||               ..:|:.    ...|..:|.   .|||||:.|.|.
Yeast     5 LKALFALLFLYTAAVNAGVIGIFNALPPPNTKPINGESPLYQCDILDKQLVEIKEVNLDPNPP-- 67

Human    47 CQLSKGQSYSVNVTFTSNIQSKSSKAVVHGILMGVPV----------PFPIPE--PDGCKSGINC 99
               .:|:    |:|.::|  .:..:.:..|..:.|.|          .|.:.|  .|....|::|
Yeast    68 ---VRGE----NLTISAN--GEVFETIEEGAYIDVEVRLGYIRLLSQTFDLCETLEDNDIEGLSC 123

Human   100 PIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQSLFC 140
            ||:..: |:....:.:..|.|..|.||..:...:|:..:.|
Yeast   124 PIEPGE-YNIKKIVEIPGEVPPGKYVVVARAYTEKDDLITC 163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPC2	NP_001350617.1	Npc2_like	24..145	CDD:238458	31/132 (23%)
NPC2	NP_010237.1	PG-PI_TP	44..168	CDD:238459	23/110 (21%)