Protein Alignment NPC2 and Npc2b

DIOPT Version :9

• Sequence 1: NP_001350617.1
• Gene: NPC2 / 10577
• HGNCID: 14537
• Length: 174
• Species: Homo sapiens
• Sequence 2: NP_650331.1
• Gene: Npc2b / 41710
• FlyBaseID: FBgn0038198
• Length: 159
• Species: Drosophila melanogaster
• Alignment Length: 122
• Identity: 33/122 - (27%)
• Similarity: 59/122 - (48%)
• Gaps: 12/122 - (9%)

Human    36 EVNVSPCPTQPCQLSKGQSYSVNVTFTSNIQSKSSKAVVHGILMGVPVPFP----------IPEP 90
            :|::|.||...|.|.:....|:.:........:...:.:.||::.||:|||          |.:.
  Fly    38 DVSISNCPKSKCILKRNTEASIQMKIRPERDFQELTSDIQGIILDVPLPFPGYYGTSACPHIYDE 102

Human    91 DGCKSGINCPIQKDKTYSYLNKLPVKSEYPSIKLVVEWQLQDDKNQSLFCWEIPVQI 147
            .|.|. :.||::..:.|:|.|...:...||::.|.:.|.| .||:....|::||.:|
  Fly   103 AGEKK-VGCPLKAGQVYTYKNSFKILPVYPTVSLEIHWGL-GDKHGDAACFQIPAKI 157

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPC2	NP_001350617.1	Npc2_like	24..145	CDD:238458	31/118 (26%)
Npc2b	NP_650331.1	Npc2_like	23..155	CDD:238458	31/118 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4063
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG49115
OrthoDB	1	1.010	-	-		D1612792at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11306
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.890