Protein Alignment SLU7 and Slu7

DIOPT Version :10

• Sequence 1: NP_001351446.1
• Gene: SLU7 / 10569
• HGNCID: 16939
• Length: 601
• Species: Homo sapiens
• Sequence 2: NP_651659.2
• Gene: Slu7 / 43427
• FlyBaseID: FBgn0039626
• Length: 574
• Species: Drosophila melanogaster
• Alignment Length: 596
• Identity: 305/596 - (51%)
• Similarity: 385/596 - (64%)
• Gaps: 61/596 - (10%)

Human    29 LSGSKEMSLEEPKKMTREDWRKKKELEEQRKLGNAPAEVDEEGKDINPHIPQYISSVPWYIDPSK 93
            ||...:.:.|||||.:||||||.|||||.||.|.|||.|||||:|||||||||||:.|||.. |.
  Fly    15 LSKHDQDAEEEPKKKSREDWRKAKELEEARKAGTAPAAVDEEGRDINPHIPQYISNAPWYYG-SA 78

Human    94 RPTLKHQRPQPEKQKQFSSSGEWYKR---GVKENSIITKYRKGACENCGAMTHKKKDCFERPRRV 155
            .|||||||||.|.::     |:..||   |:....||||:||||||||||:|||:|||.||||:|
  Fly    79 GPTLKHQRPQHEDEQ-----GQLDKRAPKGLNTARIITKFRKGACENCGAVTHKRKDCLERPRKV 138

Human   156 GAKFTGTNIAPDEHVQPQLMFDYDGKRDRWNGYNPEEHMKIVEEYAKVDLAKRTLKAQKLQEELA 220
            .||:..:.:..|||:..:...:||.|||||:.|:|..|.:|:|||.||:.|||.|||:||:
  Fly   139 QAKYAESIVVHDEHLVNEAAVNYDEKRDRWSSYDPANHREIIEEYEKVEEAKRQLKAEKLK---- 199

Human   221 SGKLVEQANSPKHQWGEEEPNSQMEKDHNSEDEDEDKYADDIDMPGQNFDSKRRITVRNLRIRED 285
                    |.|..:..:||.|             ||||.|::||||...|||:||||||||||||
  Fly   200 --------NDPDAEISDEEGN-------------EDKYVDEVDMPGTKVDSKQRITVRNLRIRED 243

Human   286 IAKYLRNLDPNSAYYDPKTRAMRENPYANAGKNPDEVSYAGDNFVRYTGDTISMAQTQLFAWEAY 350
            .|||||||||||||||||||:||:||  |.....:|..:||:||||::|||.:.|..|||||||:
  Fly   244 TAKYLRNLDPNSAYYDPKTRSMRDNP--NPAVPEEEAEFAGENFVRFSGDTTAQATAQLFAWEAH 306

Human   351 DKGSEVHLQADPTKLELLYKSFKVKKEDFKEQQKESILEKYGGQEHLDAPPAELLLAQTEDYVEY 415
            .||.:|||.|:|||||||.|.::.|||.||...|..|:|||||:|||..||..|||||||:|:||
  Fly   307 GKGVDVHLLAEPTKLELLQKEYEQKKEQFKSSTKTHIVEKYGGEEHLQVPPKSLLLAQTEEYIEY 371

Human   416 SRHGTVIKGQERAVACSKYEEDVKIHNHTHIWGSYWKEGRWGYKCCHSFFKYSYCTGEAGKE--- 477
            ||.|.||||.|:..|.|.|||||.|:|||.:|||:|..||||||||.||.|.|||.|....|
  Fly   372 SRSGKVIKGVEKPKARSIYEEDVYINNHTTVWGSFWNAGRWGYKCCKSFIKNSYCVGMQEPEGYS 436

Human   478 ---IVNSEECIINEITGEESVKKPQTLME----------------LHQEKLKEEKKKKKKKKKKH 523
               ..:|......|...:...|.|:...|                ..:|::|.||||.|||.||
  Fly   437 EHHSTSSTAAATTEPAAQSQFKVPEVPPERPTSEVDSASSSEPSSSEEEEVKPEKKKTKKKSKK- 500

Human   524 RKSSSDSDDEEKKHEKLKKALNAEEARLLHVKETMQIDERKRPYNSMYETREPTEEEMEAYRMKR 588
            |:....:.::.|:..|.|:..:.::.:...:.|  ::|:|||.|||||:.:.|||:|:|.::.||
  Fly   501 REKKKKAKEQRKQKGKNKETKDKDKTKEKDIPE--ELDDRKRAYNSMYDVKAPTEDEIEEWKKKR 563

Human   589 QRPDDPMASFL 599
            .|.:|||..|:
  Fly   564 PRAEDPMLQFM 574

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLU7	NP_001351446.1	Slu7	176..449	CDD:463326	156/272 (57%)
Slu7	NP_651659.2	Slu7	160..405	CDD:463326	156/271 (58%)