DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment PRDX4 and Prx2540-2

DIOPT Version :9

Sequence 1:NP_006397.1 Gene:PRDX4 / 10549 HGNCID:17169 Length:271 Species:Homo sapiens
Sequence 2:NP_523683.1 Gene:Prx2540-2 / 36098 FlyBaseID:FBgn0033518 Length:220 Species:Drosophila melanogaster


Alignment Length:215 Identity:65/215 - (30%)
Similarity:103/215 - (47%) Gaps:33/215 - (15%)


- Green bases have known domain annotations that are detailed below.


Human    80 KISKPAPYWEGTAVIDGEFKELKLTDYRG-KYLVFFFYPLDFTFVCPTEIIAFGDRLEEFRSINT 143
            ::.:..|.:|.    |.....:|..:::| .::|.|.:|.|||.||.||:........||...||
  Fly     2 RLGQTVPNFEA----DTTKGPIKFHEWQGNSWVVLFSHPADFTPVCTTELGRIAVHQPEFAKRNT 62

Human   144 EVVACSVDSQFTHLAWIN--------TPRRQGGLGPIRIPLLSDLTHQISKDYGVYLEDS----- 195
            :.:|.|||:..:|:.|:|        .|      |....|:::|.|..::...|:..|:.     
  Fly    63 KCLAHSVDALNSHVDWVNDIKSYCLDIP------GDFPYPIIADPTRDLAVSLGMLDEEQKKDPE 121

Human   196 -GHTLRGLFIIDDKGILRQITLNDLPVGRSVDETLRLVQAFQYTDKHGEVC-PAGWKPGSE---- 254
             |.|:|.||||.....:|......:..||:|||.||.:.:.|.||:...|. ||.|.||::    
  Fly   122 VGKTIRALFIISPDHKVRLSMFYPMSTGRNVDEILRTIDSLQLTDRLKVVATPANWTPGTKVMIL 186

Human   255 -TIIPDPAGKL--KYFDKLN 271
             |:..:.|.||  |.|||::
  Fly   187 PTVTDEEAHKLFPKGFDKVS 206

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PRDX4NP_006397.1 PRX_Typ2cys 81..252 CDD:239313 55/186 (30%)
Prx2540-2NP_523683.1 AhpC 1..194 CDD:223527 58/201 (29%)
PRX_1cys 3..218 CDD:239314 65/214 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0450
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100111
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
32.710

Return to query results.
Submit another query.