Protein Alignment NOP56 and NOP56

DIOPT Version :10

• Sequence 1: NP_006383.2
• Gene: NOP56 / 10528
• HGNCID: 15911
• Length: 594
• Species: Homo sapiens
• Sequence 2: NP_013298.1
• Gene: NOP56 / 850894
• SGDID: S000004187
• Length: 504
• Species: Saccharomyces cerevisiae
• Alignment Length: 515
• Identity: 259/515 - (50%)
• Similarity: 352/515 - (68%)
• Gaps: 26/515 - (5%)

Human     5 HVLFEHAVGYALLALK-EVEEISLLQPQVEESVLNLGKFHSIVRLVAFCPFASSQVALENANAVS 68
            ::|||...|||:..:| :.::|.....:|:|.:.:.|.|..::.||:|.||..:..||||||.:|
Yeast     6 YLLFEEPTGYAVFKVKLQQDDIGSRLKEVQEQINDFGAFTKLIELVSFAPFKGAAEALENANDIS 70

Human    69 EGVVHEDLRLLLETHLP---SKKKKVLLGVGDPKIGAAIQEELGY-NCQTGGVIAEILRGVRLHF 129
            ||:|.|.|:.:|:.:||   ||||.:.|.:.|..:|.:|:||..| :|.:..:..:::||||||.
Yeast    71 EGLVSESLKAILDLNLPKASSKKKNITLAISDKNLGPSIKEEFPYVDCISNELAQDLIRGVRLHG 135

Human   130 HNLVKGLTDLSACKAQLGLGHSYSRAKVKFNVNRVDNMIIQSISLLDQLDKDINTFSMRVREWYG 194
            ..|.|||......:|||||||:||||||||:|.:.||.|||:|:||||||||||||:|||:||||
Yeast   136 EKLFKGLQSGDLERAQLGLGHAYSRAKVKFSVQKNDNHIIQAIALLDQLDKDINTFAMRVKEWYG 200

Human   195 YHFPELVKIINDNATYCRLAQFIGNRRELNEDKLEKLEE-LTMDGAKAKAILDASRSSMGMDISA 258
            :|||||.|::.||.|:.:|..||.::..||:|.|..|.. |..|...|:.::|.:|.|||.|||.
Yeast   201 WHFPELAKLVPDNYTFAKLVLFIKDKASLNDDSLHDLAALLNEDSGIAQRVIDNARISMGQDISE 265

Human   259 IDLINIESFSSRVVSLSEYRQSLHTYLRSKMSQVAPSLSALIGEAVGARLIAHAGSLTNLAKYPA 323
            .|:.|:..|:.||.||::||:.|:.||..||..|||:||.||||.:|||||:||||||||:|..|
Yeast   266 TDMENVCVFAQRVASLADYRRQLYDYLCEKMHTVAPNLSELIGEVIGARLISHAGSLTNLSKQAA 330

Human   324 STVQILGAEKALFRALKTRGNTPKYGLIFHSTFIGRAAAKNKGRISRYLANKCSIASRIDCFSEV 388
            ||||||||||||||||||:|||||||||:||.||.:|:||||||||||||||||:|||||.:||.
Yeast   331 STVQILGAEKALFRALKTKGNTPKYGLIYHSGFISKASAKNKGRISRYLANKCSMASRIDNYSEE 395

Human   389 PTSVFGEKLREQVEERLSFYETGEIPRKNLDVMKEAM--VQAEEAAAEITRKLEKQEKKRLKKEK 451
            |::|||..|::|||:||.||.||:...||...::|||  ...::.|||:....||:..|:.|.|
Yeast   396 PSNVFGSVLKKQVEQRLEFYNTGKPTLKNELAIQEAMELYNKDKPAAEVEETKEKESSKKRKLE- 459

Human   452 KRLAALALASSENSSSTPEECEEMSEKPKKKKKQKPQEVPQENGMEDPSISFSKPKKKKS 511
                       ::.....|:.|:.|:|.||:||:|..:..:::..|      .|.|||||
Yeast   460 -----------DDDEEKKEKKEKKSKKEKKEKKEKKDKKEKKDKKE------KKDKKKKS 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NOP56	NP_006383.2	NOP5NT	5..70	CDD:462382	24/65 (37%)
		Nop	175..405	CDD:460335	147/230 (64%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	458..594		16/54 (30%)
NOP56	NP_013298.1	NOP5NT	6..72	CDD:462382	25/66 (38%)
		Nop	181..413	CDD:460335	147/232 (63%)