Protein Alignment STK25 and gck-1

DIOPT Version :9

• Sequence 1: NP_001258906.1
• Gene: STK25 / 10494
• HGNCID: 11404
• Length: 426
• Species: Homo sapiens
• Sequence 2: NP_505310.2
• Gene: gck-1 / 179274
• WormBaseID: WBGene00001526
• Length: 803
• Species: Caenorhabditis elegans
• Alignment Length: 376
• Identity: 243/376 - (64%)
• Similarity: 288/376 - (76%)
• Gaps: 12/376 - (3%)

Human    11 HSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCDS 75
            :|::|||.:|||.:|||:||||||||||||.|..||||||||||:||||||||||||.|||||||
 Worm   175 NSKLDPEVIFTKQERIGRGSFGEVYKGIDNRTGRVVAIKIIDLEQAEDEIEDIQQEIQVLSQCDS 239

Human    76 PYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHRD 140
            .|:|:||||:||.:|||||||||||||||||.|.|.|:|::||.|||||||||:|||||||||||
 Worm   240 QYVTKYFGSFLKGSKLWIIMEYLGGGSALDLTKSGKLDESHIAVILREILKGLEYLHSERKIHRD 304

Human   141 IKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGITA 205
            |||||||:||.||||:||||||||||:|..||.||||:|||||||:||||:||:|||||||||||
 Worm   305 IKAANVLVSEHGDVKVADFGVAGQLTETVKKRITFVGSPFWMAPELIKQSSYDYKADIWSLGITA 369

Human   206 IELAKGEPPNSDLHPMRVLFLIPKNSPPTLEG-QHSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
            ||||.||||:|||||||||||||||.||.|:| |.|||||||||.||||||..||:|..||||:|
 Worm   370 IELANGEPPHSDLHPMRVLFLIPKNPPPVLQGSQWSKPFKEFVEMCLNKDPENRPSASTLLKHQF 434

Human   270 ITRYTKKTSFLTELIDRYKRWKSEGHGEESSSEDSDIDGEAEDGEQGPIWTFPPTIRPSPHSKLH 334
            |.| .||.|.|.:||:|...::.    ....|.|||:|.:::.|.....|.: ||:|....|...
 Worm   435 IKR-AKKNSILVDLIERAAEYRL----RTGVSSDSDLDEDSDGGGGTSKWDY-PTVRGPRVSADD 493

Human   335 KGTALHSSQKP-AEPVKRQPRSQCLSTLVR--PVFGELKEKHKQSGGSVGA 382
            .||....:.:| |:..:|.|......|:||  |....:.|:.:.|  |||:
 Worm   494 DGTVRQRTDRPRAQVDRRSPSGSPGGTIVRGSPQVAAVAEQLRNS--SVGS 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
STK25	NP_001258906.1	STKc_STK25	15..291	CDD:270810	216/276 (78%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	291..355		17/64 (27%)
gck-1	NP_505310.2	STKc_MST3_like	183..455	CDD:270786	213/272 (78%)
		S_TKc	184..435	CDD:214567	203/250 (81%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	414	1.000	Domainoid score	I367
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H48428
Inparanoid	1	1.050	451	1.000	Inparanoid score	I993
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D418754at33208
OrthoFinder	1	1.000	-	-		FOG0000324
OrthoInspector	1	1.000	-	-		otm16258
orthoMCL	1	0.900	-	-		OOG6_100860
Panther	1	1.100	-	-	LDO	PTHR48012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R966
SonicParanoid	1	1.000	-	-		X488
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	12.000