DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment STK25 and stk24

DIOPT Version :9

Sequence 1:	NP_001258906.1	Gene:	STK25 / 10494	HGNCID:	11404	Length:	426	Species:	Homo sapiens
Sequence 2:	NP_001123697.1	Gene:	stk24 / 100170450	XenbaseID:	XB-GENE-987144	Length:	424	Species:	Xenopus tropicalis

Alignment Length:	416	Identity:	301/416 - (72%)
Similarity:	344/416 - (82%)	Gaps:	19/416 - (4%)

- Green bases have known domain annotations that are detailed below.

Human    10 QHSRVDPEELFTKLDRIGKGSFGEVYKGIDNHTKEVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 74
            |..:.||||||.||::|||||||||:|||||.|::||||||||||||||||||||||||||||||
Frog    14 QSLKADPEELFRKLEKIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIEDIQQEITVLSQCD 78

Human    75 SPYITRYFGSYLKSTKLWIIMEYLGGGSALDLLKPGPLEETYIATILREILKGLDYLHSERKIHR 139
            |||:|:|:|||||.|||||||||||||||||||:||||:||.||||||||||||||||||:||||
Frog    79 SPYVTKYYGSYLKDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHR 143

Human   140 DIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDFKADIWSLGIT 204
            |||||||||||.|:||||||||||||||||||||||||||||||||||||||||.||||||||||
Frog   144 DIKAANVLLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGIT 208

Human   205 AIELAKGEPPNSDLHPMRVLFLIPKNSPPTLEGQHSKPFKEFVEACLNKDPRFRPTAKELLKHKF 269
            ||||||||||:|:||||:||||||||:||||||.:||..||||||||||:|.|||:|||||||||
Frog   209 AIELAKGEPPHSELHPMKVLFLIPKNNPPTLEGNYSKGLKEFVEACLNKEPSFRPSAKELLKHKF 273

Human   270 ITRYTKKTSFLTELIDRYKRWKSE-GHGEESS-SEDSDIDGEAEDGEQGPIWTFPPTIRPSPHSK 332
            |.|..||||:||||||||||||.| ||...|| ||:.::|..|  |.:...|.|  |.|
Frog   274 IMRSAKKTSYLTELIDRYKRWKIEQGHEASSSDSEEEEVDQAA--GSEKDYWNF--TRR------ 328

Human   333 LHKGTALHSSQKPAEP-----VKRQPRSQCLSTLVRPVFGELKEKHKQSGGSVGALEELENAFSL 392
              |....:....||:|     :.::|.||||||::.|:|.|||||.:..||:||::|||..|..|
Frog   329 --KRDLKNLEPIPAQPEEVKDIPKRPLSQCLSTIMSPLFAELKEKSQACGGNVGSIEELREAIYL 391

Human   393 AEESCPGISDKLMVHLVERVQRFSHN 418
            |||:||||||.::..|:.|:||:|.|
Frog   392 AEEACPGISDSMVSQLLIRLQRYSVN 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
STK25	NP_001258906.1	STKc_STK25	15..291	CDD:270810	242/275 (88%)
STK25	NP_001258906.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	291..355		20/70 (29%)
stk24	NP_001123697.1	STKc_MST3	19..295	CDD:270809	242/275 (88%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D152706at32523
OrthoFinder	1	1.000	-	-		FOG0000324
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X488
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.010