Protein Alignment CAP1 and capt

DIOPT Version :10

• Sequence 1: NP_006358.2
• Gene: CAP1 / 10487
• HGNCID: 20040
• Length: 475
• Species: Homo sapiens
• Sequence 2: NP_001033870.1
• Gene: capt / 45233
• FlyBaseID: FBgn0261458
• Length: 783
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 233/507 - (45%)
• Similarity: 316/507 - (62%)
• Gaps: 56/507 - (11%)

Human     4 MQNLVERLERAVGRLEAV--------SHTSDMHRGYADS----------------PSKAGAAPYV 44
            ::::.||||..|.|||..        ..|..:....|:.                ||...:...|
  Fly   298 LESICERLETLVDRLERTLTAPQPIELPTPTLPPPPAEEEEALPVFEKAETPPPPPSPPSSNMSV 362

Human    45 QAFDSLLAGPVAEYLKISKEIGGDVQKHAEMVHTGLKLERALLVTASQCQQPAENKLSDLLAPIS 109
            ..|:.::|||:::||.:|.:|||||.:|||:|.:....:...:..|:|..|||:.|.::||.|.|
  Fly   363 AGFEDIVAGPLSQYLTLSAKIGGDVAQHAELVKSAFGSQLQYVTLATQIAQPAQPKQAELLKPTS 427

Human   110 EQIKEVITFREKNRGSKLFNHLSAVSESIQALGWVAMAPKPGPYVKEMNDAAMFYTNRVLKEYKD 174
            .||..:..||||:|.|..||||||:||||.|||||.:...|||||||||||..|||||||||:|:
  Fly   428 TQISAIQDFREKHRSSPFFNHLSAISESIPALGWVCVEKTPGPYVKEMNDAGQFYTNRVLKEWKE 492

Human   175 VDKKHVDWVKAYLSIWTELQAYIKEFHTTGLAWSKTGPVAKELSGLPSGPSAGSCPPPPPP--CP 237
            .|..||:|.:|::...|||||||:::|||||.||..|          :.| ||..||||||  .|
  Fly   493 KDVTHVEWARAWVQTLTELQAYIRQYHTTGLVWSGKG----------AAP-AGGAPPPPPPGGLP 546

Human   238 PPPPVSTISC-SYESA--SRSSLFAQINQGESITHALKHVSDDMKTHKNPALKAQSGPVRSGPKP 299
            ||||:..:|. ..:||  .||:||||||||..||..||.|:.||:|||||:|       |:||.|
  Fly   547 PPPPMLDLSALKLDSAGDDRSALFAQINQGADITKGLKKVTGDMQTHKNPSL-------RTGPAP 604

Human   300 FSAP------KPQTSPSPKRATKKEPAVLELEGKKWRVENQENVSNLVIEDTELKQVAYIYKCVN 358
            |.:|      |...:||..:|  |.| |.|.:||||.:|.|:|.:.|::|:.|:..|.|::||..
  Fly   605 FKSPAQSGGSKAVAAPSAAQA--KAP-VFERDGKKWIIEYQKNNTGLLVENAEMNNVVYVFKCEG 666

Human   359 TTLQIKGKINSITVDNCKKLGLVFDDVVGIVEIINSKDVKVQVMGKVPTISINKTDGCHAYLSKN 423
            :||.:|||:|:|..|:|||..|:||.||..||.:|.:.|::||:|.|||:||:|||||..||||:
  Fly   667 STLTVKGKVNNIVFDSCKKCSLLFDSVVASVEFVNCQSVQMQVLGSVPTVSIDKTDGCQMYLSKD 731

Human   424 SLDCEIVSAKSSEMNVLIPTEGGDFNEFPVPEQFKTLWNGQKLVTTVTEIAG 475
            ||..|||::||||||:|:|.:.||:.|..:|||:||...|:.|.|...:..|
  Fly   732 SLGVEIVNSKSSEMNILLPDDSGDYTELALPEQYKTTIAGKTLKTVCVDSLG 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CAP1	NP_006358.2	CAP_N	5..62	CDD:460113	19/80 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..237		9/22 (41%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	278..319		18/46 (39%)
		CAP_C	318..473	CDD:462532	78/154 (51%)
capt	NP_001033870.1	PHA03269	6..>117	CDD:165527
		CAP_N	299..380	CDD:460113	19/80 (24%)
		CAP_C	628..780	CDD:462532	78/152 (51%)