Protein Alignment SLC9A6 and slc9a6a

DIOPT Version :10

• Sequence 1: NP_001425671.1
• Gene: SLC9A6 / 10479
• HGNCID: 11079
• Length: 731
• Species: Homo sapiens
• Sequence 2: NP_001091726.2
• Gene: slc9a6a / 792983
• ZFINID: ZDB-GENE-070424-104
• Length: 697
• Species: Danio rerio
• Alignment Length: 715
• Identity: 536/715 - (74%)
• Similarity: 597/715 - (83%)
• Gaps: 38/715 - (5%)

Human    15 VGSSPRARRLMRPLWLLLAVGVFDWAGA---SDGGGGEARAMDEEIVSEKQAEESHRQDSANLLI 76
            :||:...:.:...:|..|.|.||..|.:   ...|..|..|| |.||:||:||||||||||:|||
Zfish     1 MGSTSEMKAVAMRVWRRLPVHVFVLASSLCLCQCGAEEDSAM-ENIVTEKKAEESHRQDSADLLI 64

Human    77 FILLLTLTILTIWLFKHRRARFLHETGLAMIYGLLVGLVLRYGIHVPSDVNNVTLSCEVQSSPTT 141
            ||:||||||||||||||||.|||||||||||||||||:||||.||||||:|||||||.|.:||.|
Zfish    65 FIMLLTLTILTIWLFKHRRFRFLHETGLAMIYGLLVGVVLRYAIHVPSDINNVTLSCHVNASPAT 129

Human   142 LLVNVSGKFYEYMLKGEISSHELNNVQDNEMLRKVTFDPEVFFNILLPPIIFYAGYSLKRRHFFR 206
            ||||||||||||.|||||.::::|::||||||||||||||||||||||||||:||||||||||||
Zfish   130 LLVNVSGKFYEYTLKGEIGANKVNDIQDNEMLRKVTFDPEVFFNILLPPIIFHAGYSLKRRHFFR 194

Human   207 NLGSILAYAFLGTAISCFVIGSIMYGCVTLMKVTGQLAGDFYFTDCLLFGAIVSATDPVTVLAIF 271
            ||||||||||:||.:|||:||::|||||.|||..|.|..||:|||||.|||||||||||||||||
Zfish   195 NLGSILAYAFVGTVVSCFIIGALMYGCVMLMKKIGHLQDDFFFTDCLFFGAIVSATDPVTVLAIF 259

Human   272 HELQVDVELYALLFGESVLNDAVAIVLSSSIVAYQPAGDNSHTFDVTAMFKSIGIFLGIFSGSFA 336
            :|||||.:||||||||||||||||:|||||||||||.|||||||:..||.||.|||||:||||||
Zfish   260 NELQVDADLYALLFGESVLNDAVAVVLSSSIVAYQPTGDNSHTFEAMAMLKSFGIFLGVFSGSFA 324

Human   337 MGAATGVVTALVTKFTKLREFQLLETGLFFLMSWSTFLLAEAWGFTGVVAVLFCGITQAHYTYNN 401
            :|.|||:||||||||||||:|.||||.|||||||||||||||.||||||||||||:||||||:||
Zfish   325 LGVATGIVTALVTKFTKLRDFPLLETALFFLMSWSTFLLAEACGFTGVVAVLFCGMTQAHYTFNN 389

Human   402 LSTESQHRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPTFVVGAFVAIFLGRAANIYPLSL 466
            ||.|||.|||||||||||||||||||||||||||||||||||.|:|.||:|:||||||||||||.
Zfish   390 LSPESQDRTKQLFELLNFLAENFIFSYMGLTLFTFQNHVFNPIFIVCAFLAVFLGRAANIYPLSF 454

Human   467 LLNLGRRSKIGSNFQHMMMFAGLRGAMAFALAIRDTATYARQMMFSTTLLIVFFTVWVFGGGTTA 531
            |||||||:||.||||||||||||||||.|||:||||||||||||||||||:||||||:.|||||.
Zfish   455 LLNLGRRNKISSNFQHMMMFAGLRGAMTFALSIRDTATYARQMMFSTTLLVVFFTVWICGGGTTQ 519

Human   532 MLSCLHIRYCARLWGYRDELRHGLYPQGTHSLFGETDRVGVDSDQEH-LGVPENERRTTKAESAW 595
            ||||..|                              |||||:|.|: :|....|||:||.||||
Zfish   520 MLSCQKI------------------------------RVGVDTDHENSIGPDGVERRSTKQESAW 554

Human   596 LFRMWYNFDHNYLKPLLTHSGPPLTTTLPACCGPIARCLTSPQAYENQEQLKDDDSDLILNDGDI 660
            |||:|||||||||||:|||||||||.||||||.|:||||||||||||:.:||:.|||||||||||
Zfish   555 LFRIWYNFDHNYLKPILTHSGPPLTATLPACCSPLARCLTSPQAYENEGELKNADSDLILNDGDI 619

Human   661 SLTYGDSTVNTEPATSSAPRRFMGN---SSEDALDRELAFGDHELVIRGTRLVLPMDDSEPPLNL 722
            :|||||..|:|:...:.:....||.   :|::|||||||||||||||||||||||||||||||.|
Zfish   620 TLTYGDIAVSTDGTGAHSSGVLMGGAAVNSDEALDRELAFGDHELVIRGTRLVLPMDDSEPPLTL 684

Human   723  722
            Zfish   685  684

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC9A6	NP_001425671.1	None
slc9a6a	NP_001091726.2	Na_H_Exchanger	52..572	CDD:470090	435/549 (79%)