Protein Alignment ECI2 and CG4598

DIOPT Version :10

• Sequence 1: NP_996667.2
• Gene: ECI2 / 10455
• HGNCID: 14601
• Length: 394
• Species: Homo sapiens
• Sequence 2: NP_609322.1
• Gene: CG4598 / 34315
• FlyBaseID: FBgn0032160
• Length: 281
• Species: Drosophila melanogaster
• Alignment Length: 275
• Identity: 56/275 - (20%)
• Similarity: 101/275 - (36%)
• Gaps: 76/275 - (27%)

Human   131 GTDR---KSTGFETLVVTSEDGITKIMFNRPKKKNAINTEMYHEIMRALKAASKDDSIITVLTGN 192
            |::|   .:|...|:.|..:.||..:..||| ..|.:|.|:..::..::.....:.|...:||.:
  Fly    14 GSNRMMSTATKLTTVEVNDKTGIATLTMNRP-PVNGLNLELLQDLKSSIDEIESNKSRGLILTSS 77

Human   193 GD-YYSSGNDLTNFTDIPPGGVEEKAKNNAVLLREF-----------VGCFIDFPKPLIAVVNG- 244
            .. .:|:|.|:.           |..|.:...:|.|           .|..:    |..|.:||
  Fly    78 SSTIFSAGLDIL-----------EMYKPDKDRIRAFWTQLQDTWLALYGSSV----PTAAAINGH 127

Human   245 -PA-------------------VGISVTLLGLFDAVYASDRATFHTPFSHLGQSPEGCSSYTFPK 289
             ||                   :|::.|.||:.                    :|:...: :|..
  Fly   128 SPAGGCLLATSCEYRVMVPNFTIGLNETQLGIV--------------------APQWFMA-SFLS 171

Human   290 IMSPAKATEMLIFGKKLTAGEACAQGLVTEVF--PDSTFQKEVWTRLKAFAKLPPNALRISKEVI 352
            ::....|...|..|:..|..||...||:.|..  .:...:|.| ..:..|||:.|.|..::|:..
  Fly   172 VLPQRIAERALNQGRMFTTEEALKVGLIDETANNKEEAIEKCV-AFIGTFAKVNPLARSLTKQQF 235

Human   353 RKREREKLHAVNAEE 367
            |..:.::|.....|:
  Fly   236 RAADLQQLQNGRKED 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ECI2	NP_996667.2	ACBP	39..113	CDD:469667
		crotonase-like	142..335	CDD:119339	43/227 (19%)
		ECH-like	151..322		38/205 (19%)
		Microbody targeting signal. /evidence=ECO:0000255	392..394
CG4598	NP_609322.1	crotonase-like	27..217	CDD:119339	44/227 (19%)