Protein Alignment ECI2 and Mtpalpha

DIOPT Version :10

• Sequence 1: NP_996667.2
• Gene: ECI2 / 10455
• HGNCID: 14601
• Length: 394
• Species: Homo sapiens
• Sequence 2: NP_609299.1
• Gene: Mtpalpha / 34276
• FlyBaseID: FBgn0028479
• Length: 783
• Species: Drosophila melanogaster
• Alignment Length: 283
• Identity: 61/283 - (21%)
• Similarity: 113/283 - (39%)
• Gaps: 47/283 - (16%)

Human    97 NALGSLPKEAARQNYVDLVSSLSPSLESSSQVEPGTDRKSTG--------FETLVVTSEDGITKI 153
            :|:|.:.::...||      ..:.:|..|:|:.......||.        ..|.||   :|:..|
  Fly     8 SAVGQISRQQLLQN------KCTRALPISAQLLQRRRLMSTNPAPVANKHLHTKVV---NGVLVI 63

Human   154 MFNRPKKK-NAINTEMYHEIMRALKAASKDDSI--ITVLTGNGDYYSSGNDLTNFTDIPPGGVEE 215
            ..:.|..| |::.:|:..|..|.:|....:.::  ..:::|....:.:|.|:        |.:|.
  Fly    64 KIDSPNAKVNSLGSEVSDEFERVIKDLETNPAVNSAVLISGKPGCFVAGADI--------GMLEA 120

Human   216 -KAKNNAVLLREFVGCFID----FPKPLIAVVNGPAVGISVTL-LGLFDAVYASDRAT-FHTPFS 273
             :....|.|:........|    ..||::|.::|..:|..:.| |.....:...|..| ...|..
  Fly   121 CQTAEEATLISHGAQVMFDRMERSKKPIVAAISGVCLGGGLELALACHYRIATKDSKTKLGLPEV 185

Human   274 HLGQSPEGCSSYTFPKIMSPAKATEMLIFGKKLTAGEACAQGLVTEVFPD-----------STFQ 327
            .||..|.|..:...||:.|...|.:|.:.||::.|..|...|:| ::..|           :|.:
  Fly   186 MLGLLPGGGGTVRLPKLTSVPTALDMELTGKQVRADRAKRLGIV-DLLVDPLGPGLQPAEQNTIE 249

Human   328 KEVWTRLKAFAKLPPNALRISKE 350
            ....|.::....|....||:::|
  Fly   250 YLEKTAVQVANDLASGKLRVNRE 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ECI2	NP_996667.2	ACBP	39..113	CDD:469667	4/15 (27%)
		crotonase-like	142..335	CDD:119339	47/213 (22%)
		ECH-like	151..322		41/180 (23%)
		Microbody targeting signal. /evidence=ECO:0000255	392..394
Mtpalpha	NP_609299.1	fa_ox_alpha_mit	38..775	CDD:131494	54/247 (22%)