Protein Alignment TAB1 and Pp2C1

DIOPT Version :9

• Sequence 1: NP_006107.1
• Gene: TAB1 / 10454
• HGNCID: 18157
• Length: 504
• Species: Homo sapiens
• Sequence 2: NP_001284867.1
• Gene: Pp2C1 / 31404
• FlyBaseID: FBgn0022768
• Length: 1427
• Species: Drosophila melanogaster
• Alignment Length: 560
• Identity: 99/560 - (17%)
• Similarity: 170/560 - (30%)
• Gaps: 192/560 - (34%)

Human    65 YGVFNGYDGNRVTNFVAQRLSAELLLGQLNAEHAEADVRRVLLQAFDVVERSFLESIDDALAEKA 129
            :|:::|:.|.....|..:.|..|::..:......:.||.|.:.:.:.....:....
  Fly   292 FGIYDGHGGPEAALFAKEHLMLEIVKQKQFWSDQDEDVLRAIREGYIATHFAMWRE--------- 347

Human   130 SLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTNRALLCKST 194
              |.:.|.....|            |.|      .|..|.||.:...|:|:.:||.:..:|
  Fly   348 --QEKWPRTANGH------------LST------AGTTATVAFMRREKIYIGHVGDSGIVL---- 388

Human   195 VDGLQ--------VTQLNVDHTTENEDELFRLSQLG--------------------LDAGKIKQ- 230
              |.|        ...|..||..|:..|..|:.:.|                    :..|.|::
  Fly   389 --GYQNKGERNWRARPLTTDHKPESLAEKTRIQRSGGNVAIKSGVPRVVWNRPRDPMHRGPIRRR 451

Human   231 --VGIICGQESTRRIGDYKVKYGYTDIDLLSAAKSKPIIAEPEIHGAQPLDGVTGFLVLMSEGLY 293
              |..|......|.:||.   :.|.     |..|...:..:|::...:........|:..::||:
  Fly   452 TLVDEIPFLAVARSLGDL---WSYN-----SRFKEFVVSPDPDVKVVKINPSTFRCLIFGTDGLW 508

Human   294 KALEAAHGPGQANQE--IAAMIDTEFAKQTSLDAVAQAVVDRVKRIHSDTFASGGERARFCPRHE 356
            ..:.|........:|  |..:::.:.....|     :|:||:..:    |:|:...||
  Fly   509 NVVTAQEAVDSVRKEHLIGEILNEQDVMNPS-----KALVDQALK----TWAAKKMRA------- 557

Human   357 DMTLLVRNFGYPLGEMSQP-TPSPAPAAGGR---------------------------------- 386
            |.|.:|.....|....:.| ||:.:|:|..|
  Fly   558 DNTSVVTVILTPAARNNSPTTPTRSPSAMARDNDLEVELLLEEDDEELPTLDVENNYPDFLIEEH 622

Human   387 VYPVSVPYSS-----------------------------------------AQSTSKTSVTLSLV 410
            .|.:..|||:                                         .::.|...:..||.
  Fly   623 EYVLDQPYSALAKRHSPPEAFRNFDYFDVDEDELDEDEETVEEDEEEEEEEEETKSVGILQQSLF 687

Human   411 MPS---QGQMVNGAHSASTLDEATP----------TLTNQSPTLTLQSTNTHTQSSSSSSDGGLF 462
            .|.   :...:|.:.|..|..|..|          ||...|.|...:.||.....:.||.|
  Fly   688 NPRKTWRKSTINNSWSGVTEPEPEPDPEPDRIDVLTLDMYSHTSIDKGTNYGGSIAQSSID---- 748

Human   463 RSRPAHSLPPGEDGRVEPYVD----FAEFYRLWSVDHGEQ 498
               ||.:....|...:|.:::    |||.|.....:..||
  Fly   749 ---PAETAENRELSELEQHLESSYSFAESYNSLLNEQEEQ 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TAB1	NP_006107.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		PP2C	69..334	CDD:395385	52/297 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	430..478		13/57 (23%)
Pp2C1	NP_001284867.1	PP2Cc	256..567	CDD:238083	60/333 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900