Protein Alignment ACAA2 and yip2

DIOPT Version :9

• Sequence 1: NP_006102.2
• Gene: ACAA2 / 10449
• HGNCID: 83
• Length: 397
• Species: Homo sapiens
• Sequence 2: NP_523528.1
• Gene: yip2 / 34313
• FlyBaseID: FBgn0040064
• Length: 398
• Species: Drosophila melanogaster
• Alignment Length: 395
• Identity: 235/395 - (59%)
• Similarity: 294/395 - (74%)
• Gaps: 1/395 - (0%)

Human     2 ALLRGVFVVAAKRTPFGAYGGLLKDFTATDLSEFAAKAALSAGKVSPETVDSVIMGNVLQSSS-D 65
            |..:|:::||||||.||.:||.||....|.|...||||||.|..:..|.||:||:|||:.||| |
  Fly     3 AATKGIYIVAAKRTAFGTFGGSLKGINQTQLQTTAAKAALDAAGLKGEQVDTVIVGNVIASSSTD 67

Human    66 AIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGTESMSQAPYCVR 130
            .||:.|||||..|:|.|.|||.|||||||||||||||.|:|.|..|::.|.||.|:|||:|:..|
  Fly    68 GIYVPRHVGLNCGVPIEKPALGINRLCGSGFQSIVNGAQDILVGGAKIALTGGVENMSQSPFIAR 132

Human   131 NVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREECDKYALQSQQRWKAAND 195
            ||||||.||:...|||:||..|||.:.:||||:||||||.::|||||..|:::|.||:.|:....
  Fly   133 NVRFGTTLGASYNLEDALWAGLTDTYCKLPMALTAENLADQYKISRERVDEFSLLSQKNWEKGQK 197

Human   196 AGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKDGTVTAGNASGVADGAGAV 260
            .|.||.|:.||::|.|..:....||||.||:||:|.|.|||.:|||:|.||||.|||:.|||.||
  Fly   198 EGAFNAEITPIKLKVKGKEVDFVVDEHPRPKTTIEGLNKLPSLFKKNGVVTAGTASGICDGASAV 262

Human   261 IIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVPAISGALKKAGLSLKDMDLVEVNEAFAP 325
            |:|||:|:|::|..||||:|.:...|..|.||||||||||...||.:|..|:|:||:|:|||||.
  Fly   263 IVASEEALKEYNLKPLARLVAFSFVGVKPEIMGIGPVPAIQNVLKVSGKKLEDIDLIEINEAFAA 327

Human   326 QYLAVERSLDLDISKTNVNGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIA 390
            |.||...:|.||.||.||||||||||||||.||||||.||||||:|:..||.:||||||||||||
  Fly   328 QTLACADALKLDTSKLNVNGGAIALGHPLGASGSRITGHLVHELQRKKLKYGIGSACIGGGQGIA 392

Human   391 VIIQS 395
            :::::
  Fly   393 LLLEA 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACAA2	NP_006102.2	thiolase	8..394	CDD:238383	233/386 (60%)
yip2	NP_523528.1	PRK05790	6..398	CDD:180261	234/392 (60%)
		thiolase	9..397	CDD:238383	233/387 (60%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146885
Domainoid	1	1.000	298	1.000	Domainoid score	I1459
eggNOG	1	0.900	-	-		E1_COG0183
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4456
Inparanoid	1	1.050	465	1.000	Inparanoid score	I1549
Isobase	1	0.950	-	0	Normalized mean entropy	S770
OMA	1	1.010	-	-		QHG58994
OrthoDB	1	1.010	-	-		D1129049at2759
OrthoFinder	1	1.000	-	-		FOG0000432
OrthoInspector	1	1.000	-	-		oto89496
orthoMCL	1	0.900	-	-		OOG6_104226
Panther	1	1.100	-	-	LDO	PTHR18919
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3557
SonicParanoid	1	1.000	-	-		X5028
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	17	16.750