Protein Alignment TMEM147 and CG5861

DIOPT Version :10

• Sequence 1: NP_116024.1
• Gene: TMEM147 / 10430
• HGNCID: 30414
• Length: 224
• Species: Homo sapiens
• Sequence 2: NP_609789.1
• Gene: CG5861 / 34965
• FlyBaseID: FBgn0015338
• Length: 227
• Species: Drosophila melanogaster
• Alignment Length: 220
• Identity: 108/220 - (49%)
• Similarity: 149/220 - (67%)
• Gaps: 6/220 - (2%)

Human     1 MTLFHFGNCFALAYFPYFITYKCSGLSEYNAFWKCVQAGVTYLFVQLCKMLFLATFF----PTWE 61
            |||:|||||.|| ..||:.|||.||||||.|||||||||..|:|.||.|||.|||||    |: .
  Fly     1 MTLYHFGNCVAL-LTPYYFTYKYSGLSEYGAFWKCVQAGGIYIFTQLVKMLVLATFFYSDAPS-S 63

Human    62 GGIYDFIGEFMKASVDVADLIGLNLVMSRNAGKGEYKIMVAALGWATAELIMSRCIPLWVGARGI 126
            .|.::|..|.::.|:|:|||:|..|::||..|||..|::.|.|||||||:|:||.|.|||||||.
  Fly    64 SGEFNFFAEILRCSMDIADLLGFALILSRIPGKGHSKLITAGLGWATAEVILSRGIMLWVGARGT 128

Human   127 EFDWKYIQMSIDSNISLVHYIVASAQVWMITRYDLYHTFRPAVLLLMFLSVYKAFVMETFVHLCS 191
            ||.|.||...::||:.||.:|..:..:|:.||:||....:|.|.||:.::|:|...:|..:|:.:
  Fly   129 EFSWIYILKCLESNVLLVQHITTATLIWLFTRHDLNKALKPLVSLLLAVTVFKGVWLEGMLHILT 193

Human   192 LGSWAALLARAVVTGLLALSTLALY 216
            :|.|..:..:|:|..::...||.:|
  Fly   194 IGPWLTVAVKALVAAVIGFCTLHIY 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMEM147	NP_116024.1	DUF2053	2..155	CDD:462890	87/156 (56%)
CG5861	NP_609789.1	DUF2053	2..157	CDD:462890	87/156 (56%)