Protein Alignment YAP1 and CG3356

DIOPT Version :9

• Sequence 1: XP_005271435.1
• Gene: YAP1 / 10413
• HGNCID: 16262
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_611896.1
• Gene: CG3356 / 37876
• FlyBaseID: FBgn0034989
• Length: 1122
• Species: Drosophila melanogaster
• Alignment Length: 423
• Identity: 76/423 - (17%)
• Similarity: 119/423 - (28%)
• Gaps: 175/423 - (41%)

Human   117 ALTPQHVRA---HSSPASLQLGAVSPGTLTPTGVV---SGPAAT--------------------- 154
            |.||:.:||   ..:..|.|||..:|.||...|||   .|...|
  Fly   496 AFTPKFIRAVWFKLAAESTQLGFSAPLTLISKGVVPKHQGVDRTIPLLATFCMLFGRLLPTLHDV 560

Human   155 ------------PTAQHLRQSSFEIPDDVPLPAGWEMAKT----SSG---------------QRY 188
                        .|..|:|...|.|.:.:      :|:||    |.|               .|.
  Fly   561 EFVENKLLLQVHSTINHVRLMPFSIAEII------QMSKTLKDISMGLVELAFPETRSNLANYRK 619

Human   189 FLNHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAMTQDGEIYYINHKN 253
            .|.|     |..|.:| :..|..:.|        |::|.....|    .|..|:|..:.:....:
  Fly   620 VLGH-----TEADDKK-LRHQKQIWA--------NLLNVVVFVL----NQIHTRDLRLGFCPEDH 666

Human   254 KTTSWLDPRLDPRFGKAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKE 318
                |...|||              .|:.:|..|.
  Fly   667 ----WTVTRLD--------------LPLDRPTDLP------------------------------ 683

Human   319 RLRLKQQELLRQVRP-QAMRNI-NPSTANSPKCQELALRSQLPTLEQDGGTQNPVSSPGMSQELR 381
               |.....||.:|| |.:|:. .....|.|                          |..::::|
  Fly   684 ---LTHSSRLRGIRPFQPIRDFTREDFENGP--------------------------PMSTKQIR 719

Human   382 TMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEM----------DTGDTIN 436
            ::|.....||:  ..::.|.....|.::.|...|......||.....:          |..|.:.
  Fly   720 SITILREIPFV--VPFNKRVSILQSLVAASKMRVQGNMQAFLQGPSVLITVRRSHLYEDAYDKLR 782

Human   437 QSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGM 469
            ....|..  ||...::.:....:|...::|.|:
  Fly   783 PDNEPDL--RFKFRIQFVSSLGLDEAGIDGGGV 813

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YAP1	XP_005271435.1	WW	174..203	CDD:238122	10/47 (21%)
		WW	232..261	CDD:366073	5/28 (18%)
CG3356	NP_611896.1	HECTc	766..1120	CDD:238033	8/50 (16%)
		HECTc	788..1119	CDD:214523	5/28 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900