Protein Alignment YAP1 and yki

DIOPT Version :9

• Sequence 1: XP_005271435.1
• Gene: YAP1 / 10413
• HGNCID: 16262
• Length: 510
• Species: Homo sapiens
• Sequence 2: NP_001350857.1
• Gene: yki / 37851
• FlyBaseID: FBgn0034970
• Length: 418
• Species: Drosophila melanogaster
• Alignment Length: 313
• Identity: 97/313 - (30%)
• Similarity: 140/313 - (44%)
• Gaps: 106/313 - (33%)

Human    54 IVHVRGDSETDLEALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQAST----DAGT 114
            :|.|..|::.:|:|||::|:||..|..|..:|:|:||||:|||.||.| ||||..|.    |||:
  Fly    57 VVRVNQDTDDNLQALFDSVLNPGDAKRPLQLPLRMRKLPNSFFTPPAP-SHSRANSADSTYDAGS 120

Human   115 AGAL----------------------------TPQ-------HVRAHSSPASLQLGAVSPGTLTP 144
            ..::                            :||       |.||.|||||||.. .:....:.
  Fly   121 QSSINIGNKASIVQQPDGQSPIAAIPQLQIQPSPQHSRLAIHHSRARSSPASLQQN-YNVRARSD 184

Human   145 TGVVSGPAATPTAQ----------------------------------------------HLRQS 163
            ....:.|.|.|::|                                              |.:|.
  Fly   185 AAAANNPNANPSSQQQPAGPTFPENSAQEFPSGAPASSAIDLDAMNTCMSQDIPMSMQTVHKKQR 249

Human   164 SFEIPDDV-------PLPAGWEMAKTSSGQRYFLNHIDQTTTWQDPR-----------KAMLSQM 210
            |:::...:       .||.|||.|||:.||.|:|||..::|.|:|||           ...:.|.
  Fly   250 SYDVISPIQLNRQLGALPPGWEQAKTNDGQIYYLNHTTKSTQWEDPRIQYRQQQQILMAERIKQN 314

Human   211 NVTAPTSPPVQQNMMNSASGPLPDGWEQAMTQDGEIYYINHKNKTTSWLDPRL 263
            :|...|.......:.|:. ||||||||||:|:.|::|:|||.::||||.|||:
  Fly   315 DVLQTTKQTTTSTIANNL-GPLPDGWEQAVTESGDLYFINHIDRTTSWNDPRM 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YAP1	XP_005271435.1	WW	174..203	CDD:238122	16/28 (57%)
		WW	232..261	CDD:366073	18/28 (64%)
yki	NP_001350857.1	HUL4	<261..>404	CDD:227354	46/107 (43%)
		WW	266..295	CDD:395320	16/28 (57%)
		WW	335..364	CDD:395320	18/28 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165159007
Domainoid	1	1.000	54	1.000	Domainoid score	I11301
eggNOG	1	0.900	-	-		E1_COG5021
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1006566at2759
OrthoFinder	1	1.000	-	-		FOG0003509
OrthoInspector	1	1.000	-	-		otm40799
orthoMCL	1	0.900	-	-		OOG6_107951
Panther	1	1.100	-	-	LDO	PTHR17616
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4834
SonicParanoid	1	1.000	-	-		X2881
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.740