Protein Alignment YAP1 and Yap1

DIOPT Version :10

• Sequence 1: XP_005271435.1
• Gene: YAP1 / 10413
• HGNCID: 16262
• Length: 510
• Species: Homo sapiens
• Sequence 2: XP_006509915.1
• Gene: Yap1 / 22601
• MGIID: 103262
• Length: 494
• Species: Mus musculus
• Alignment Length: 510
• Identity: 453/510 - (88%)
• Similarity: 473/510 - (92%)
• Gaps: 16/510 - (3%)

Human     1 MDPGQQPPPQPAPQGQGQPPSQPPQGQGPPSGPGQPAPAATQAAPQAPPAGHQIVHVRGDSETDL 65
            |:|.||||||||           |||..|||    .:||.|.|||.|||||||:|||||||||||
Mouse     1 MEPAQQPPPQPA-----------PQGPAPPS----VSPAGTPAAPPAPPAGHQVVHVRGDSETDL 50

Human    66 EALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPA 130
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    51 EALFNAVMNPKTANVPQTVPMRLRKLPDSFFKPPEPKSHSRQASTDAGTAGALTPQHVRAHSSPA 115

Human   131 SLQLGAVSPGTLTPTGVVSGPAATPTAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHIDQ 195
            |||||||||||||.:||||||||.|.||||||||||||||||||||||||||||||||||||.||
Mouse   116 SLQLGAVSPGTLTASGVVSGPAAAPAAQHLRQSSFEIPDDVPLPAGWEMAKTSSGQRYFLNHNDQ 180

Human   196 TTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAMTQDGEIYYINHKNKTTSWLD 260
            ||||||||||||||:||.||.||.|.|.:|||||||||||||||||||||:||||||||||||||
Mouse   181 TTTWQDPRKAMLSQLNVPAPASPAVPQTLMNSASGPLPDGWEQAMTQDGEVYYINHKNKTTSWLD 245

Human   261 PRLDPRFGKAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQ 325
            |||||||||||||||:||||||||||||||||||||:||.:||||||::||||||||||||||||
Mouse   246 PRLDPRFGKAMNQRITQSAPVKQPPPLAPQSPQGGVLGGGSSNQQQQIQLQQLQMEKERLRLKQQ 310

Human   326 ELLRQVRPQAMRNINPSTANSPKCQELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDP 390
            ||.|||||||:|||||||||:|||||||||||||||||||||.|.||||||||||||||||||||
Mouse   311 ELFRQVRPQAIRNINPSTANAPKCQELALRSQLPTLEQDGGTPNAVSSPGMSQELRTMTTNSSDP 375

Human   391 FLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIP 455
            ||||||||||||||||||||||||:||||||||||||||||||||:||||||||:||||||||:|
Mouse   376 FLNSGTYHSRDESTDSGLSMSSYSIPRTPDDFLNSVDEMDTGDTISQSTLPSQQSRFPDYLEALP 440

Human   456 GTNVDLGTLEGDGMNIEGEELMPSLQEALSSDILNDMESVLAATKLDKESFLTWL 510
            ||||||||||||.||||||||||||||||||:|| |:||||||||||||||||||
Mouse   441 GTNVDLGTLEGDAMNIEGEELMPSLQEALSSEIL-DVESVLAATKLDKESFLTWL 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YAP1	XP_005271435.1	WW	174..203	CDD:238122	27/28 (96%)
		WW	231..263	CDD:197736	30/31 (97%)
Yap1	XP_006509915.1	WW	159..188	CDD:238122	27/28 (96%)
		WW	216..248	CDD:197736	30/31 (97%)