DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MYL9 and CG31802

DIOPT Version :9

Sequence 1:	NP_006088.2	Gene:	MYL9 / 10398	HGNCID:	15754	Length:	172	Species:	Homo sapiens
Sequence 2:	NP_724103.1	Gene:	CG31802 / 318949	FlyBaseID:	FBgn0051802	Length:	186	Species:	Drosophila melanogaster

Alignment Length:	168	Identity:	53/168 - (31%)
Similarity:	84/168 - (50%)	Gaps:	15/168 - (8%)

- Green bases have known domain annotations that are detailed below.

Human     3 SKRAKAKTTKKRPQRATSNVFAMFDQSQIQ--EFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNP 65
            |.|||   ..|:|:..|      ||.|..|  :.|:||::.|....|||:.::|...:.:||..|
  Fly    23 SSRAK---KSKKPKLPT------FDLSLSQKVDIKKAFDLFDTQCTGFIETKELRVAIRALGFEP 78

Human    66 TDEYLEGMMSE----APGPINFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLREL 126
            ..|.::.||.|    ..|.|.|..||.:...|:...|....:..||:.||::.:|.|...:|:.:
  Fly    79 KKEDIKRMMDEIDKDKTGRIAFNDFLYLMRLKMAEKDSNQDMMKAFSFFDDDRTGGISFLNLKRV 143

Human   127 LTTMGDRFTDEEVDEMYREAPIDKKGNFNYVEFTRILK 164
            ...:|::.||||:.||..||.:...|..:..||..::|
  Fly   144 AKELGEQLTDEELQEMIDEANVSGDGEVSKEEFLNLIK 181

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MYL9	NP_006088.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20		6/16 (38%)
MYL9	NP_006088.2	FRQ1	19..169	CDD:227455	47/152 (31%)
CG31802	NP_724103.1	PTZ00183	38..185	CDD:185503	45/144 (31%)
		EFh	46..108	CDD:238008	20/61 (33%)
		EFh	119..181	CDD:238008	19/61 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910