DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment MYL9 and CG30378

DIOPT Version :9

Sequence 1:	NP_006088.2	Gene:	MYL9 / 10398	HGNCID:	15754	Length:	172	Species:	Homo sapiens
Sequence 2:	NP_724628.1	Gene:	CG30378 / 246577	FlyBaseID:	FBgn0050378	Length:	148	Species:	Drosophila melanogaster

Alignment Length:	143	Identity:	37/143 - (25%)
Similarity:	84/143 - (58%)	Gaps:	8/143 - (5%)

- Green bases have known domain annotations that are detailed below.

Human    28 QSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASLGKNPTDEYLEGMMSEA----PGPINFTMFLT 88
            ::||:|.:|||::.|:.|.|::..:.|..::.:||::.|:..:..:.:|:    .|.:.|..||.
  Fly     7 EAQIEEIREAFSLYDKERSGWVSVQQLGGVMRALGESLTEAEIYDLANESNADFGGQVQFKDFLY 71

Human    89 MFGEKLNGTDPEDVIRNAFACFD-EEASGF-IHEDHLRELLTTMGDRFTDEEVDEMYREAPIDKK 151
            :..::|...:....::.||..|| .|.:.| |:|  :|.::|.:|::.::|::.|::::...||.
  Fly    72 VMSKRLEEQNSLVCLKQAFKIFDRSEVNSFTINE--IRMVMTNLGEKMSEEDLRELFQDIDQDKD 134

Human   152 GNFNYVEFTRILK 164
            |..::.||...::
  Fly   135 GKISFNEFVTAMR 147

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
MYL9	NP_006088.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..20
MYL9	NP_006088.2	FRQ1	19..169	CDD:227455	37/143 (26%)
CG30378	NP_724628.1	PTZ00184	1..148	CDD:185504	37/143 (26%)
		EFh	12..74	CDD:238008	16/61 (26%)
		EFh	86..147	CDD:238008	18/62 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910