Protein Alignment TUBB4B and betaTub60D

DIOPT Version :9

• Sequence 1: NP_006079.1
• Gene: TUBB4B / 10383
• HGNCID: 20771
• Length: 445
• Species: Homo sapiens
• Sequence 2: NP_523842.2
• Gene: betaTub60D / 37888
• FlyBaseID: FBgn0003888
• Length: 454
• Species: Drosophila melanogaster
• Alignment Length: 449
• Identity: 402/449 - (89%)
• Similarity: 430/449 - (95%)
• Gaps: 8/449 - (1%)

Human     1 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEA------TGGKY 59
            |||||:||||||||||||||||:||:|||||..|.|.|||||||||::||||||      :||||
  Fly     1 MREIVNLQAGQCGNQIGAKFWEIISEEHGIDSNGIYVGDSDLQLERVSVYYNEASAVTRSSGGKY 65

Human    60 VPRAVLVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVVRKEA 124
            ||||:|:|||||||:||||||:||:|||||||:||||||||||||||||||||||:||||||||.
  Fly    66 VPRAILLDLEPGTMESVRSGPYGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELVDNVLDVVRKEC 130

Human   125 ESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVVPSPKVSDTVVEPYNATLSV 189
            |:||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||||:
  Fly   131 ENCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTYSVVPSPKVSDTVVEPYNATLSI 195

Human   190 HQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLA 254
            |||||||||||||||||||||||||||::.|:|||||||||.|||||||||||||||||||||||
  Fly   196 HQLVENTDETYCIDNEALYDICFRTLKVSNPSYGDLNHLVSLTMSGVTTCLRFPGQLNADLRKLA 260

Human   255 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRG 319
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   261 VNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRG 325

Human   320 RMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRGLKMSATFIGNSTAIQELFKRISEQ 384
            ||||||||||||.||||||||||||||||||||||||||:|||||:|||||:|||||||||||||
  Fly   326 RMSMKEVDEQMLAVQNKNSSYFVEWIPNNVKTAVCDIPPKGLKMSSTFIGNTTAIQELFKRISEQ 390

Human   385 FTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEEGEFEEEAEEE 443
            |:||||||||||||||||||||||||||||||||||||||||:|||::  ||:.|..:|
  Fly   391 FSAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQEATADD--EFDPEVNQE 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB4B	NP_006079.1	PLN00220	1..427	CDD:215107	394/431 (91%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	426..445		8/18 (44%)
betaTub60D	NP_523842.2	PLN00220	1..450	CDD:215107	402/449 (90%)
		beta_tubulin	2..432	CDD:276956	392/429 (91%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D259639at33208
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.830