Protein Alignment TUBB4A and betaTub97EF

DIOPT Version :9

• Sequence 1: NP_001276052.1
• Gene: TUBB4A / 10382
• HGNCID: 20774
• Length: 495
• Species: Homo sapiens
• Sequence 2: NP_001163753.1
• Gene: betaTub97EF / 43359
• FlyBaseID: FBgn0003890
• Length: 457
• Species: Drosophila melanogaster
• Alignment Length: 444
• Identity: 390/444 - (87%)
• Similarity: 422/444 - (95%)
• Gaps: 2/444 - (0%)

Human    52 MREIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVL 116
            |||||||||||||||||:||||:|||||||||.|.|||:|.||.|||:||||||:.|.|||||||
  Fly     1 MREIVHLQAGQCGNQIGSKFWEIISDEHGIDPNGYYHGESALQHERIDVYYNEASSGKYVPRAVL 65

Human   117 VDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCL 181
            :|||||||||||..|.||:|||||||:||||||||||||||||||||:|:||:|:|||:|.||||
  Fly    66 IDLEPGTMDSVRQSPVGQLFRPDNFVYGQSGAGNNWAKGHYTEGAELIDSVLEVLRKESEGCDCL 130

Human   182 QGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVEN 246
            |||||.||||||||||:|||||||||||:||||||:||||||||||||||||||||||:||||||
  Fly   131 QGFQLAHSLGGGTGSGLGTLLISKIREEYPDRIMNSFSVVPSPKVSDTVVEPYNATLSIHQLVEN 195

Human   247 TDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVPF 311
            ||||:|||||||||||||||||::|||||||||||.|||||||||||||||||||||||||||||
  Fly   196 TDETFCIDNEALYDICFRTLKLSSPTYGDLNHLVSVTMSGVTTCLRFPGQLNADLRKLAVNMVPF 260

Human   312 PRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMKE 376
            ||||||||||||||::||||||||||.|||||||||||||.|||||||||||||.:|||.|||||
  Fly   261 PRLHFFMPGFAPLTAKGSQQYRALTVAELTQQMFDAKNMMTACDPRHGRYLTVACIFRGPMSMKE 325

Human   377 VDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMFR 441
            ||.||.:||||||||||||||||||.||||||||||||:||||||||||||:|||||||||||||
  Fly   326 VDTQMYNVQSKNSSYFVEWIPNNVKVAVCDIPPRGLKMSATFIGNSTAIQEIFKRISEQFTAMFR 390

Human   442 RKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATA-EEGEF-EEEAEEE 493
            ||||||||||||||||||||||||||||:|||||||:||| :|.|| :|:||:|
  Fly   391 RKAFLHWYTGEGMDEMEFTEAESNMNDLISEYQQYQEATADDEVEFDDEQAEQE 444

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB4A	NP_001276052.1	PLN00220	52..478	CDD:215107	379/425 (89%)
		beta_tubulin	53..477	CDD:276956	377/423 (89%)
betaTub97EF	NP_001163753.1	PLN00220	1..444	CDD:215107	389/442 (88%)
		beta_tubulin	2..426	CDD:276956	377/423 (89%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53784
OrthoDB	1	1.010	-	-		D259639at33208
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100137
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X99
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	8	7.930