Protein Alignment TUBB4A and CG7794

DIOPT Version :9

• Sequence 1: NP_001276052.1
• Gene: TUBB4A / 10382
• HGNCID: 20774
• Length: 495
• Species: Homo sapiens
• Sequence 2: NP_650674.1
• Gene: CG7794 / 42159
• FlyBaseID: FBgn0038565
• Length: 455
• Species: Drosophila melanogaster
• Alignment Length: 451
• Identity: 151/451 - (33%)
• Similarity: 256/451 - (56%)
• Gaps: 15/451 - (3%)

Human    54 EIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGN--YVPRAVL 116
            ||:.:..||.|.||....||:...||||...|..   :...::...:.:.|.|...  ..||.|:
  Fly     6 EIIQIHIGQAGVQIANACWELFCLEHGILANGRL---TQSPMDDSFLTFFEFTSHQPCVQPRLVM 67

Human   117 VDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCL 181
            :|.||..:|.:|:|.:..:|.||..:.|:..:|:|:|:|:....:||:|..::.:|:.|:.|..|
  Fly    68 IDTEPTVIDEIRTGSYRNLFHPDTLITGKDDSGSNFARGYNLMASELLDRSMNAIRRVADRCRNL 132

Human   182 QGFQLTHSLGGGTGSGMGTLLISKIREEFPDRI-MNTFSVVPSPKVSDTVVEPYNATLSVHQLVE 245
            :||.:..::|||:|||:||.::.::.|:|..:: :..|.|.|||.:|..:||||||.|:.|..::
  Fly   133 RGFLVFRAIGGGSGSGLGTRIMERLVEDFGKKMTVVEFLVYPSPSISPVIVEPYNALLAAHFSMD 197

Human   246 NTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 310
            ..|.::.:|||||||||..||.:..|||.:||.:::..:|..|...||.|......::|..|:||
  Fly   198 CADVSFIVDNEALYDICANTLNVPAPTYTNLNRIIAQVVSSFTASQRFGGGSTVSFQELQTNLVP 262

Human   311 FPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMK 375
            :||:|:.:..:|||......|:..::..:||.|.|...|.|..|:|.||:|:....::||.::..
  Fly   263 YPRIHYPLINYAPLVPISHSQFVNMSTAQLTGQCFQMSNQMVRCNPSHGKYMASVLLYRGDIAPN 327

Human   376 EVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPP---RGLKMAAT-----FIGNSTAIQELFKRI 432
            |::..:.:::...|..||:|.|...|..|..:||   .|..:|.|     .|.|:|.|:..:.|:
  Fly   328 EINTALENIKRNRSFRFVDWSPTGFKIGVSPMPPYYVPGGDLAPTNRACVAISNNTNIRIAWCRL 392

Human   433 SEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQYQDATAEEGEFEEEAEEE 493
            ..:|..:::|:||::.|.|||::|..|.||..|:..||.:|.:. ||:|.....:.:.||:
  Fly   393 VNKFDKLYQRRAFVYHYVGEGLEEGNFNEASENICQLVHDYLEV-DASAPTSRRDSDPEED 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB4A	NP_001276052.1	PLN00220	52..478	CDD:215107	146/434 (34%)
		beta_tubulin	53..477	CDD:276956	146/433 (34%)
CG7794	NP_650674.1	alpha_tubulin	5..436	CDD:276955	146/432 (34%)
		PTZ00335	6..439	CDD:185562	147/436 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810