Protein Alignment TUBB4A and gammaTub37C

DIOPT Version :9

• Sequence 1: NP_001276052.1
• Gene: TUBB4A / 10382
• HGNCID: 20774
• Length: 495
• Species: Homo sapiens
• Sequence 2: NP_001260565.1
• Gene: gammaTub37C / 35199
• FlyBaseID: FBgn0010097
• Length: 457
• Species: Drosophila melanogaster
• Alignment Length: 439
• Identity: 152/439 - (34%)
• Similarity: 257/439 - (58%)
• Gaps: 23/439 - (5%)

Human    54 EIVHLQAGQCGNQIGAKFWEVISDEHGIDPTGTYHGDSDLQLERINVYYNEATGGNYVPRAVLVD 118
            ||:.||.||||||||.:||:.:..||||.|.|.....:....:|.:|::.:|...:|:|||||:|
  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFATDGQDRKDVFFYQADDNHYIPRAVLID 68

Human   119 LEPGTMDSVRSGPFGQIFRPDNFVFGQ--SGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDCL 181
            |||..::::.:.|:.:::..:|....:  .|||||||.| :::|.::.:.|.|::.:||:..|.|
  Fly    69 LEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASG-FSQGEKVQEEVFDILDREADGSDSL 132

Human   182 QGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPS-PKVSDTVVEPYNATLSVHQLVE 245
            :||.|.||:.||||||||:.::.::.|.||.:::.|:||.|: .::||.||:|||:.|::.:|.:
  Fly   133 EGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRLTK 197

Human   246 NTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 310
            ..|....:||.||..|....|.:.|||:..:|:|||..||..||.||:|..:|.:|..|..:::|
  Fly   198 CADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASLIP 262

Human   311 FPRLHFFMPGFAPLTS--RGSQQYRALTVPELTQQMFDAKNMM-AACDPRHGR--YLTVAAVFRG 370
            .|:|||.|.|:.||.|  ......|..||.::.:::...|||| :|...:..|  ::::..:.:|
  Fly   263 TPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQCFVSILNIIQG 327

Human   371 RMSMKEVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGL-------KMAATFIGNSTAIQEL 428
            .:...:|.:.:..::.:..:.|:.|.|.:::.|:    ||..       |::...:.|.|.|..|
  Fly   328 EVDPSQVHKSLQRIRERKLANFIPWGPASIQVAL----PRSSPYVQSAHKVSGLMMANHTGISSL 388

Human   429 FKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTE---AESNMNDLVSEYQ 474
            |||...|:..:.:|.|||..:..|.|.:.:.||   |...::.||.||:
  Fly   389 FKRALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYE 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB4A	NP_001276052.1	PLN00220	52..478	CDD:215107	152/439 (35%)
		beta_tubulin	53..477	CDD:276956	152/439 (35%)
gammaTub37C	NP_001260565.1	PLN00222	1..447	CDD:215108	152/439 (35%)
		gamma_tubulin	4..436	CDD:276957	150/436 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810