Protein Alignment TUBB4A and CG32396

DIOPT Version :9

• Sequence 1: NP_001276052.1
• Gene: TUBB4A / 10382
• HGNCID: 20774
• Length: 495
• Species: Homo sapiens
• Sequence 2: NP_729172.1
• Gene: CG32396 / 117406
• FlyBaseID: FBgn0052396
• Length: 462
• Species: Drosophila melanogaster
• Alignment Length: 458
• Identity: 240/458 - (52%)
• Similarity: 318/458 - (69%)
• Gaps: 20/458 - (4%)

Human    52 MREIVHLQAGQCGNQIGAKFWEVISDEHGID-PTGTYHGDSDLQLERINVYYNEATGGNYVPRAV 115
            |||||.||.|..||.||..||.|||.|||:| .:|.:.|.|.||||||||::|......:..|.:
  Fly     1 MREIVTLQIGGAGNAIGDSFWHVISHEHGVDYASGRFGGTSPLQLERINVFFNATASKRFYARTI 65

Human   116 LVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDAVLDVVRKEAESCDC 180
            |:|.|..|:..:.:.  .|::||:|||.|...||||:|:|::|:||.::|.||:..|:|.||.|.
  Fly    66 LIDTEASTIQRLNAS--SQLYRPENFVAGSESAGNNFARGYHTDGAAILDQVLENTRREVESVDS 128

Human   181 LQGFQLTHSLGGGTGSGMGTLLISKIREEFPDRIMNTFSVVPSPKVSDTVVEPYNATLSVHQLVE 245
            ||||||.||:|||||||:.:|::..:.|::||.::..:..:|||.:|..|||||||.||...||.
  Fly   129 LQGFQLLHSIGGGTGSGLTSLIMEALVEQYPDNLLCNYVTIPSPNMSQVVVEPYNALLSTPALVN 193

Human   246 NTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCLRFPGQLNADLRKLAVNMVP 310
            |:..|:|:|||||:.||.|.|||....|..:||:|:.||||:||||||||||||.|||:.|||||
  Fly   194 NSHLTFCLDNEALFQICNRNLKLKMSGYEHINHIVALTMSGITTCLRFPGQLNAGLRKIYVNMVP 258

Human   311 FPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDAKNMMAACDPRHGRYLTVAAVFRGRMSMK 375
            ||||||.:||||||.:...||:...||.||.||:|.:.|::.|.|.|.|:.||.|.:||||||.:
  Fly   259 FPRLHFLIPGFAPLVTCKQQQFSKGTVSELVQQIFYSNNLLCAIDLRKGKLLTAAGIFRGRMSPR 323

Human   376 EVDEQMLSVQSKNSSYFVEWIPNNVKTAVCDIPPRGLKMAATFIGNSTAIQELFKRISEQFTAMF 440
            |||:.|..|::||.:.||:|||||:|||:||||||||||:||||||:||||.||:|:.:...:|.
  Fly   324 EVDQLMTGVRNKNINNFVDWIPNNIKTAICDIPPRGLKMSATFIGNTTAIQTLFQRLLDASMSML 388

Human   441 RRKAFLHWYTGEGMDEMEFTEAESNMNDLVSEYQQY---------------QDATAEEGEFEEEA 490
            ||||.|||||||||:|.||.:|:..:..::.:|:..               :..:||.|  ||||
  Fly   389 RRKAHLHWYTGEGMEEQEFQDAQQELQAIIDDYRSSAEGEDSGGGGGGGGGRSGSAESG--EEEA 451

Human   491 EEE 493
            ..|
  Fly   452 TPE 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBB4A	NP_001276052.1	PLN00220	52..478	CDD:215107	232/441 (53%)
		beta_tubulin	53..477	CDD:276956	231/439 (53%)
CG32396	NP_729172.1	PTZ00010	1..421	CDD:240228	231/421 (55%)
		beta_tubulin	2..425	CDD:276956	231/424 (54%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D962471at2759
OrthoFinder	1	1.000	-	-		FOG0000096
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11588
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920