Protein Alignment TUBA1B and alphaTub84B

DIOPT Version :9

• Sequence 1: NP_006073.2
• Gene: TUBA1B / 10376
• HGNCID: 18809
• Length: 451
• Species: Homo sapiens
• Sequence 2: NP_476772.1
• Gene: alphaTub84B / 40848
• FlyBaseID: FBgn0003884
• Length: 450
• Species: Drosophila melanogaster
• Alignment Length: 451
• Identity: 435/451 - (96%)
• Similarity: 445/451 - (98%)
• Gaps: 1/451 - (0%)

Human     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRA 65
            |||||||||||||||||||||||||||||||||||||||||:|||||||||||||||||||||||
  Fly     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTVGGGDDSFNTFFSETGAGKHVPRA 65

Human    66 VFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCT 130
            |||||||||:|||||||||||||||||||||||||||||||||||||||:|||||||||||||||
  Fly    66 VFVDLEPTVVDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIVDLVLDRIRKLADQCT 130

Human   131 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTL 195
            ||||||:||||||||||||||||||||||||||||||||:|||||||||||||||||||||||||
  Fly   131 GLQGFLIFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFAIYPAPQVSTAVVEPYNSILTTHTTL 195

Human   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLV 260
            ||||||||||||||||||||||||||||||||||||.||||||||||||||||||||||||||||
  Fly   196 EHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLIGQIVSSITASLRFDGALNVDLTEFQTNLV 260

Human   261 PYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLLYRGDVVP 325
            |||||||||.||||||||||||||||||||||||||||||||||||||||||||||:||||||||
  Fly   261 PYPRIHFPLVTYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCMLYRGDVVP 325

Human   326 KDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390
            ||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||||
  Fly   326 KDVNAAIATIKTKRTIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAIAEAWAR 390

Human   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEEVGVDSVEGEGEEEGEEY 451
            ||||||||||||||||||||||||||||||||||:|||||||||||:||.:||| |..|||
  Fly   391 LDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDLAALEKDYEEVGMDSGDGEG-EGAEEY 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBA1B	NP_006073.2	PTZ00335	1..440	CDD:185562	427/438 (97%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	432..451		12/18 (67%)
alphaTub84B	NP_476772.1	PTZ00335	1..439	CDD:185562	426/437 (97%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	435	1.000	Domainoid score	I577
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	904	1.000	Inparanoid score	I376
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54134
OrthoDB	1	1.010	-	-		D275336at33208
OrthoFinder	1	1.000	-	-		FOG0000082
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100108
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2309
SonicParanoid	1	1.000	-	-		X95
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.810