Protein Alignment TUBA1B and gammaTub37C

DIOPT Version :9

• Sequence 1: NP_006073.2
• Gene: TUBA1B / 10376
• HGNCID: 18809
• Length: 451
• Species: Homo sapiens
• Sequence 2: NP_001260565.1
• Gene: gammaTub37C / 35199
• FlyBaseID: FBgn0010097
• Length: 457
• Species: Drosophila melanogaster
• Alignment Length: 442
• Identity: 140/442 - (31%)
• Similarity: 240/442 - (54%)
• Gaps: 19/442 - (4%)

Human     3 ECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVF 67
            |.|::.:||.|.|||...|:..||||||.|||.:....|  .|.|..:.||.:.....::||||.
  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPDGVLEDFAT--DGQDRKDVFFYQADDNHYIPRAVL 66

Human    68 VDLEPTVIDEVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIIDLVLDRIRKLADQCT 130
            :||||.||:.:.|..|.:|::.|.:...|.  .|.||:|.| ::.|:::.:.|.|.:.:.||...
  Fly    67 IDLEPRVINNIMTSPYSKLYNQENVFLSKHGGGAGNNWASG-FSQGEKVQEEVFDILDREADGSD 130

Human   131 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYP-APQVSTAVVEPYNSILTTHTT 194
            .|:||::.||..||||||..|.::||||..:.||....:|::| ..::|..||:|||||||....
  Fly   131 SLEGFVLCHSIAGGTGSGMGSYVLERLSERFPKKLIQTYSVFPNQDEISDVVVQPYNSILTLKRL 195

Human   195 LEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNL 259
            .:.:|...::||.|:..|....|.|:.||:|.:|.|:|.|:|..|.:||:...:|.:|.....:|
  Fly   196 TKCADSVVVLDNTALNRIATERLHIQTPTFTQINNLVSTIMSLSTTTLRYPSYMNNNLIGLTASL 260

Human   260 VPYPRIHFPLATYAPVIS--AEKAYHEQLSVAEITNACFEPANQMVKC--DPRHGK-YMACCLLY 319
            :|.|::||.:..|.|::|  ..|....:.:|.::.....:|.|.||..  |.:..: :::...:.
  Fly   261 IPTPQLHFLMTGYTPLMSDCETKTSVRKTTVLDVMRRLLQPKNMMVSALTDKQSRQCFVSILNII 325

Human   320 RGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTAI 384
            :|:|.|..|:.::..|:.::...|:.|.|...:|.:....|.|.....::.:     |::|.|.|
  Fly   326 QGEVDPSQVHKSLQRIRERKLANFIPWGPASIQVALPRSSPYVQSAHKVSGL-----MMANHTGI 385

Human   385 AEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSE---AREDMAALEKDYE 433
            :..:.|...::|.:..:.||:..:..|.|.:.:.:|   ||:.:..|.::||
  Fly   386 SSLFKRALAQYDKLRKRNAFLDNFRRESMFQDDLTELDIARDTVDCLVQEYE 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBA1B	NP_006073.2	PTZ00335	1..440	CDD:185562	140/442 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	432..451		2/2 (100%)
gammaTub37C	NP_001260565.1	PLN00222	1..447	CDD:215108	140/442 (32%)
		gamma_tubulin	4..436	CDD:276957	138/439 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810