Protein Alignment TUBA1B and gammaTub23C

DIOPT Version :9

• Sequence 1: NP_006073.2
• Gene: TUBA1B / 10376
• HGNCID: 18809
• Length: 451
• Species: Homo sapiens
• Sequence 2: NP_476804.1
• Gene: gammaTub23C / 33501
• FlyBaseID: FBgn0260639
• Length: 475
• Species: Drosophila melanogaster
• Alignment Length: 471
• Identity: 149/471 - (31%)
• Similarity: 247/471 - (52%)
• Gaps: 31/471 - (6%)

Human     3 ECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETGAGKHVPRAVF 67
            |.|::.:||.|.|||...|:..||||||.|.|.:  :.....|.|..:.||.:.....::||||.
  Fly     4 EIITLQLGQCGNQIGFEFWKRLCLEHGISPSGVL--EDFANDGLDRKDVFFYQADDDHYIPRAVL 66

Human    68 VDLEPTVIDEVRTGTYRQLFHPEQLITGKE--DAANNYARGHYTIGKEIIDLVLDRIRKLADQCT 130
            :||||.||:.:....|.:|::||.:...|.  .|.||:|.| |:.|:::.:.|.|.|.:.||...
  Fly    67 LDLEPRVINTIMGSVYSKLYNPENVYLSKHGGGAGNNWASG-YSQGEKLQEEVFDIIDREADGSD 130

Human   131 GLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYP-APQVSTAVVEPYNSILTTHTT 194
            .|:||::.||..||||||..|.:||||:..|.||....||::| ..::|..||:||||:||....
  Fly   131 SLEGFILCHSIAGGTGSGMGSFIMERLADRYPKKLIQTFSVFPNQDEISDVVVQPYNSMLTLKRL 195

Human   195 LEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNL 259
            ...:|...::||.|:..|....|.|:.|:::.:|.|:|.|:|..|.:||:...:|.:|......|
  Fly   196 TTAADSVVVLDNTALNRIACDRLHIQNPSFSQINNLVSTIMSVSTTTLRYPSYMNNNLIGLTAPL 260

Human   260 VPYPRIHFPLATYAPVISAEKAYHEQL------SVAEITNACFEPANQMVKCDP---RHGKYMAC 315
            :|.|::||.:..|.|:.|....:.:||      :|.::.....:|.|.||...|   .|..|::.
  Fly   261 IPTPQLHFLMTGYTPLTSDSDIHTQQLVNVRKTTVLDVMRRLLQPKNMMVSTGPDKSNHHCYISI 325

Human   316 CLLYRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSN 380
            ..:.:|:|.|..|:.::..|:.::..||:.|.||..:|.::...|.|.....::.:     ||:|
  Fly   326 LNIIQGEVDPTQVHKSLQRIRDRKMAQFIPWGPTSIQVALSRSSPYVQSNHRVSGL-----MLAN 385

Human   381 TTAIAEAWARLDHKFDLMYAKRAFVHWYVGEGM---EEGEFSEAREDM--------AALEKDYEE 434
            .|:|...:.|..:::|.:..:.||:..:..|.:   :..|..|:||.:        ||..:||.:
  Fly   386 HTSICSLFERALNQYDKLRKRGAFLDQFRREDIFKDDLNELDESRETVDCLVQEYEAATREDYMQ 450

Human   435 VGVDSVEGEGEEEGEE 450
            ..|....|..:.:.|:
  Fly   451 FSVKRGNGPVDSKSED 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBA1B	NP_006073.2	PTZ00335	1..440	CDD:185562	147/459 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	432..451		4/19 (21%)
gammaTub23C	NP_476804.1	PLN00222	1..451	CDD:215108	146/454 (32%)
		gamma_tubulin	4..440	CDD:276957	142/443 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810