Protein Alignment TUBA1B and CG32396

DIOPT Version :9

• Sequence 1: NP_006073.2
• Gene: TUBA1B / 10376
• HGNCID: 18809
• Length: 451
• Species: Homo sapiens
• Sequence 2: NP_729172.1
• Gene: CG32396 / 117406
• FlyBaseID: FBgn0052396
• Length: 462
• Species: Drosophila melanogaster
• Alignment Length: 467
• Identity: 161/467 - (34%)
• Similarity: 248/467 - (53%)
• Gaps: 35/467 - (7%)

Human     1 MRECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIG--GGD-----DSFNTFFSETGA 58
            |||.:::.:|.||..||::.|.:...|||:        |...|  ||.     :..|.||:.|.:
  Fly     1 MREIVTLQIGGAGNAIGDSFWHVISHEHGV--------DYASGRFGGTSPLQLERINVFFNATAS 57

Human    59 GKHVPRAVFVDLEPTVIDEVRTGTYRQLFHPEQLITGKEDAANNYARGHYTIGKEIIDLVLDRIR 123
            .:...|.:.:|.|.:.|..:...:  ||:.||..:.|.|.|.||:|||::|.|..|:|.||:..|
  Fly    58 KRFYARTILIDTEASTIQRLNASS--QLYRPENFVAGSESAGNNFARGYHTDGAAILDQVLENTR 120

Human   124 KLADQCTGLQGFLVFHSFGGGTGSGFTSLLMERLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSI 188
            :..:....||||.:.||.|||||||.|||:||.|...|.......:...|:|.:|..||||||::
  Fly   121 REVESVDSLQGFQLLHSIGGGTGSGLTSLIMEALVEQYPDNLLCNYVTIPSPNMSQVVVEPYNAL 185

Human   189 LTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLT 253
            |:|...:.:|...|.:||||::.||.|||.::...|.::|.:::..:|.||..|||.|.||..|.
  Fly   186 LSTPALVNNSHLTFCLDNEALFQICNRNLKLKMSGYEHINHIVALTMSGITTCLRFPGQLNAGLR 250

Human   254 EFQTNLVPYPRIHFPLATYAPVISAEKAYHEQLSVAEITNACFEPANQMVKCDPRHGKYMACCLL 318
            :...|:||:||:||.:..:||:::.::....:.:|:|:....|...|.:...|.|.||.:....:
  Fly   251 KIYVNMVPFPRLHFLIPGFAPLVTCKQQQFSKGTVSELVQQIFYSNNLLCAIDLRKGKLLTAAGI 315

Human   319 YRGDVVPKDVNAAIATIKTKRSIQFVDWCPTGFKVGINYQPPTVVPGGDLAKVQRAVCMLSNTTA 383
            :||.:.|::|:..:..::.|....||||.|...|..|...||        ..::.:...:.||||
  Fly   316 FRGRMSPREVDQLMTGVRNKNINNFVDWIPNNIKTAICDIPP--------RGLKMSATFIGNTTA 372

Human   384 IAEAWARLDHKFDLMYAKRAFVHWYVGEGMEEGEFSEAREDMAALEKDYEE--VGVDSVEGEG-- 444
            |...:.||......|..::|.:|||.||||||.||.:|::::.|:..||..  .|.||..|.|
  Fly   373 IQTLFQRLLDASMSMLRRKAHLHWYTGEGMEEQEFQDAQQELQAIIDDYRSSAEGEDSGGGGGGG 437

Human   445 ------EEEGEE 450
                  .|.|||
  Fly   438 GGRSGSAESGEE 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TUBA1B	NP_006073.2	PTZ00335	1..440	CDD:185562	154/447 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	432..451		10/29 (34%)
CG32396	NP_729172.1	PTZ00010	1..421	CDD:240228	150/437 (34%)
		beta_tubulin	2..425	CDD:276956	151/440 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5023
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810