DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment HMG20B and jigr1

DIOPT Version :9

Sequence 1:	NP_006330.2	Gene:	HMG20B / 10362	HGNCID:	5002	Length:	317	Species:	Homo sapiens
Sequence 2:	NP_001097920.1	Gene:	jigr1 / 43093	FlyBaseID:	FBgn0039350	Length:	336	Species:	Drosophila melanogaster

Alignment Length:	187	Identity:	36/187 - (19%)
Similarity:	69/187 - (36%)	Gaps:	56/187 - (29%)

- Green bases have known domain annotations that are detailed below.

Human    57 PKGKKRKKILPNGPKAPV--TG----------------YVRFLNERREQIRTRHPDLPFPEITKM 103
            |||:.|       |:|..  ||                |.|.....::::...|   .:.:|...
  Fly    13 PKGRGR-------PRATYAQTGEFDLGLIREYRSHPVLYDRSNKRFKDKLYVAH---IWEQIAHK 67

Human   104 LGAEWSKLQ---PTEKQRYLDEAEREKQQYMKELRAYQQSEAYKMCTEKIQEKK------IKKED 159
            ||.:.:.::   .|.:.||..|..|.:.....:...:...|:.:...:.|:.::      :|:||
  Fly    68 LGYDATSIRERMTTLRNRYNIEKRRVENGLSTQSSQWPLFESLQFLGDHIRPRRSFKNMSVKEED 132

Human   160 -----------SSSGLMNTLLNGHKGGDCDGFSTFD----VPIFTEEFLDQNKAREA 201
                       .|:|.||::.:..:    |....||    :|:.|...:..|.:.||
  Fly   133 EETYEVDDCRSDSNGHMNSIKDELE----DDSEIFDCEQALPVTTVLGIPLNNSDEA 185

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
HMG20B	NP_006330.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..71		4/13 (31%)
HMG20B	NP_006330.2	HMGB-UBF_HMG-box	70..135	CDD:238686	15/85 (18%)
jigr1	NP_001097920.1	MADF	33..118	CDD:214738	12/87 (14%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900