Protein Alignment HMG20B and Sox21b

DIOPT Version :10

• Sequence 1: NP_006330.2
• Gene: HMG20B / 10362
• HGNCID: 5002
• Length: 317
• Species: Homo sapiens
• Sequence 2: NP_001261829.1
• Gene: Sox21b / 39569
• FlyBaseID: FBgn0042630
• Length: 587
• Species: Drosophila melanogaster
• Alignment Length: 322
• Identity: 58/322 - (18%)
• Similarity: 105/322 - (32%)
• Gaps: 94/322 - (29%)

Human     2 SHGPKQPGAAAAP-----AGGKAPGQH----------------------GGFVVTVKQERGEGPR 39
            |:|..|.|..:|.     |||.|...|                      ...:..:.|..|....
  Fly   158 SNGSSQLGGGSASGAGSVAGGAANSHHSAPASSSVMAAAAAAHLHHNSQASPISNLHQNMGSLMN 222

Human    40 AGEKGSHEEEPVKKRGWPKGKKRKKILPNGPKAPVTGYVRFLNERREQIRTRHPDLPFPEITKML 104
            :|...|.....:..:...|.:..:.|     |.|:..::.:...:|.:|...:|.:...||:|.|
  Fly   223 SGSSASDVFFSLMIQNTTKRQNEEHI-----KRPMNAFMVWSRLQRRKIAQDNPKMHNSEISKRL 282

Human   105 GAEWSKLQPTEKQRYLDEAEREKQQYMKELRAY------------QQSEAYKMCTEKIQEKKIKK 157
            ||||..|...||:.::|||:|.:..:|||...|            :....|.|....:..:.::.
  Fly   283 GAEWKLLTEEEKRPFIDEAKRLRAMHMKEHPDYKYRPRRKPKALRRDGYPYPMPYPSVPVEALRA 347

Human   158 -----------------------EDSSSGLMNTLLNGH-------------KGGDCDGFSTF-DV 185
                                   :.|:.......|:|.             .......:|.: |.
  Fly   348 GITPGYFAPGPTAAAYHLGSHLGQTSTPTTTQATLSGQMDKFALERSSYLSNSSQASAYSAYLDP 412

Human   186 PIFTEEFLDQNKAREAELRRLRKMNVAFE-------EQNAVLQRHTQSMSSARERLEQELAL 240
            .:.|:.:.|....::      |..|.||:       :|:|......|.....:::.:|:..|
  Fly   413 SVLTKAYFDSKMYQD------RAANYAFDISKIYGAQQHAAAHHQQQQQQQQQQQQQQQQLL 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HMG20B	NP_006330.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		16/95 (17%)
		HMG-box_HMG20B	69..147	CDD:438834	26/89 (29%)
Sox21b	NP_001261829.1	HMG-box_SoxB	246..325	CDD:438790	25/83 (30%)