Protein Alignment HMG20B and Hmg-2

DIOPT Version :9

• Sequence 1: NP_006330.2
• Gene: HMG20B / 10362
• HGNCID: 5002
• Length: 317
• Species: Homo sapiens
• Sequence 2: NP_611553.1
• Gene: Hmg-2 / 37407
• FlyBaseID: FBgn0026582
• Length: 376
• Species: Drosophila melanogaster
• Alignment Length: 348
• Identity: 87/348 - (25%)
• Similarity: 151/348 - (43%)
• Gaps: 73/348 - (20%)

Human    31 KQERGEGPRAGEKGSHEEEPVKKRGWPKGKKRKKI------LPNGPKAPVTGYVRFLNERREQIR 89
            |..:|:......||.|.:..:       |.:.||:      :...||.|:.|||||:|:|||::|
  Fly    38 KPAKGKKKAKNPKGRHSDSDI-------GSELKKLAQRRINVAGAPKMPLNGYVRFMNDRREELR 95

Human    90 TRHPDLPFPEITKMLGAEWSKLQPTEKQRYLDEAEREKQQYMKELRAYQQSEAYKMCTEKIQEKK 154
            ...|.....|.|:::|.||.:|....|..|::.|.::|..|.::|:.:.:.....:..|..:.||
  Fly    96 REQPQRTALEHTRIIGEEWHQLPEERKLPYIEAAAKDKAIYQEQLQMFLKEHPEIVANELAKAKK 160

Human   155 IKKEDSS---------SGLMNTLLNGHK-----GGDCDG-------------------------- 179
            ..|.|.|         |.|........|     ..|.|.
  Fly   161 ATKLDGSPKEKTPKGESALGKAKKTKAKPVKRQSEDPDDVPLAKVKRAQTPPPPTPPAAPVQPPP 225

Human   180 ------------FSTFDVPIFTEEFLDQNKAREAELRRLRKMNVAFEEQNAVLQRHTQSMSSARE 232
                        ....::||:|.||::.|::.|.|||.|||.....|:|||||::|..:..:...
  Fly   226 SSVPPATPAPRPLQPGEIPIYTNEFIEHNRSTENELRTLRKAKTDLEQQNAVLEQHVDNTKAGYA 290

Human   233 RLEQELA--LEERRTLALQQQLQAVRQALTASFASLPVPGTGET-PTLGTLDFYMARLHGAIERD 294
            ::..|:.  :||.:  .|:..|:|:||.|.|:...:.:|....: |::|.:|.|:..|.|.:.:
  Fly   291 KVMGEVTELMEENQ--RLETYLRALRQKLVAALGGISMPPLEPSGPSVGNIDKYIRHLAGLVTQ- 352

Human   295 PAQHEKLIVRIKEILAQVASEHL 317
            |:  ...:::.:|.|.:|.:..|
  Fly   353 PS--NVTLIKAREALRKVDTSSL 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HMG20B	NP_006330.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		8/45 (18%)
		HMGB-UBF_HMG-box	70..135	CDD:238686	25/64 (39%)
Hmg-2	NP_611553.1	HMGB-UBF_HMG-box	76..141	CDD:238686	25/64 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8882
eggNOG	1	0.900	-	-		E1_COG5648
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4452
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45555
OrthoDB	1	1.010	-	-		D1458939at2759
OrthoFinder	1	1.000	-	-		FOG0003510
OrthoInspector	1	1.000	-	-		otm41200
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR46040
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3288
SonicParanoid	1	1.000	-	-		X2882
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.970