| Sequence 1: | NP_001381482.1 | Gene: | TLR6 / 10333 | HGNCID: | 16711 | Length: | 796 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_523797.1 | Gene: | Toll-7 / 37272 | FlyBaseID: | FBgn0034476 | Length: | 1446 | Species: | Drosophila melanogaster |
| Alignment Length: | 907 | Identity: | 195/907 - (21%) |
|---|---|---|---|
| Similarity: | 331/907 - (36%) | Gaps: | 290/907 - (31%) |
- Green bases have known domain annotations that are detailed below.
|
Human 57 LDMSQNYIAELQVSDMSFLSELTVLRLSHNRIQLLDLSVF----------KFNQDLEYLDLSHNQ 111
Human 112 LQKIS----CHPIVSFRHLDLSFNDFKALPICKEFGNLSQLNFLGLSAMKLQKLDLLPIAHLHLS 172
Human 173 YILLDLRNYYIKENETESLQILNAKTLHLVFHPTSLFAIQVNISVNTLGCLQLTNIKLNDDNCQV 237
Human 238 FIKFLSELTRG-----STLL-------NFTLNHIE-TTWKCLVRVFQFLWPKPVEYLNIYN--LT 287
Human 288 IIE-SIREEDFTYSKTTLKALTIEHITNQVFLFSQTALYTVFSEMNI---MMLTISDTPF--IHM 346
Human 347 LCPHAPSTFKFLNFTQNVFTDSIFEKCSTLVKLE--------------------TLILQKNGLKD 391
Human 392 L----FK-----VGL-------------MTKDMPSLEILDVSWN---SLESGRHKEN-------- 423
Human 424 ------------CTWVESIVVLNLSSNMLTDSVFRCLPPRIKVLDLHSNKIKSVPKQVVKLE--- 473
Human 474 ALQELNVAFNSLTDLPGCGSFSSLSVLIIDHNSVSH--PSA----------DFFQS------CQK 520
Human 521 MR-----------SIKAGDNPFQCTCELREFVKNIDQVSSEVLEGWPD--SYKCDYPESYRGS-- 570
Human 571 -PLKDFHMSELSC----NITLLIVTIGATMLVLAVTVTSLC-IYLDLPWYLRMV-CQWTQTRRRA 628
Human 629 RNIPLEE----LQRN----LQFHAFISYSEHDSAWVKSELVPYLEKE------DIQI-------- 671
Human 672 -CLHERNFVPGKSIVE-----NIINCIEKSYKSIFVLSPNFVQSEWCHYELYFAHHNLFHEGSNN 730
Human 731 LILILLEPIPQNSIPNKYHKLKALMTQRTYLQWPKEKSKRGLFWANIRAAFNMKLTLVTENN 792 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| TLR6 | NP_001381482.1 | LRR 1 | 54..77 | 4/19 (21%) | |
| LRR 2 | 78..101 | 8/32 (25%) | |||
| LRR 3 | 102..122 | 9/23 (39%) | |||
| LRR 4 | 123..147 | 6/23 (26%) | |||
| LRR 5 | 148..168 | 2/19 (11%) | |||
| LRR 6 | 169..196 | 3/26 (12%) | |||
| LRR 7 | 197..219 | 6/21 (29%) | |||
| LRR 8 | 220..250 | 8/34 (24%) | |||
| LRR 9 | 251..277 | 9/33 (27%) | |||
| LRR 10 | 278..303 | 6/27 (22%) | |||
| LRR 11 | 304..330 | 8/25 (32%) | |||
| LRR 12 | 331..354 | 5/27 (19%) | |||
| LRR 13 | 355..378 | 6/22 (27%) | |||
| LRR 14 | 379..404 | 11/66 (17%) | |||
| LRR 15 | 405..429 | 9/46 (20%) | |||
| LRR 16 | 430..450 | 6/19 (32%) | |||
| LRR 17 | 451..474 | 8/25 (32%) | |||
| LRR 18 | 475..496 | 3/20 (15%) | |||
| LRR 19 | 497..520 | 6/40 (15%) | |||
| Toll-7 | NP_523797.1 | LRR_8 | 135..201 | CDD:290566 | 3/6 (50%) |
| leucine-rich repeat | 136..159 | CDD:275380 | |||
| leucine-rich repeat | 160..190 | CDD:275380 | |||
| LRR_8 | 189..259 | CDD:290566 | 18/64 (28%) | ||
| leucine-rich repeat | 191..214 | CDD:275380 | 4/19 (21%) | ||
| leucine-rich repeat | 215..248 | CDD:275380 | 8/32 (25%) | ||
| LRR_RI | 247..501 | CDD:238064 | 76/333 (23%) | ||
| LRR_8 | 247..308 | CDD:290566 | 22/104 (21%) | ||
| leucine-rich repeat | 249..273 | CDD:275380 | 9/23 (39%) | ||
| leucine-rich repeat | 274..297 | CDD:275380 | 9/66 (14%) | ||
| LRR_8 | 297..356 | CDD:290566 | 20/75 (27%) | ||
| leucine-rich repeat | 298..321 | CDD:275380 | 10/32 (31%) | ||
| leucine-rich repeat | 322..345 | CDD:275380 | 7/29 (24%) | ||
| LRR_8 | 345..406 | CDD:290566 | 16/69 (23%) | ||
| leucine-rich repeat | 346..371 | CDD:275380 | 8/24 (33%) | ||
| leucine-rich repeat | 372..395 | CDD:275380 | 6/31 (19%) | ||
| leucine-rich repeat | 396..419 | CDD:275380 | 7/26 (27%) | ||
| LRR_8 | 419..478 | CDD:290566 | 13/64 (20%) | ||
| leucine-rich repeat | 420..443 | CDD:275380 | 4/23 (17%) | ||
| leucine-rich repeat | 444..467 | CDD:275380 | 6/27 (22%) | ||
| LRR_RI | 466..622 | CDD:238064 | 37/157 (24%) | ||
| leucine-rich repeat | 468..488 | CDD:275380 | 2/19 (11%) | ||
| LRR_8 | 491..549 | CDD:290566 | 14/57 (25%) | ||
| leucine-rich repeat | 491..514 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 515..536 | CDD:275380 | 3/20 (15%) | ||
| leucine-rich repeat | 539..562 | CDD:275380 | 7/22 (32%) | ||
| leucine-rich repeat | 563..585 | CDD:275380 | 2/22 (9%) | ||
| leucine-rich repeat | 586..626 | CDD:275380 | 13/40 (33%) | ||
| leucine-rich repeat | 627..653 | CDD:275380 | 4/25 (16%) | ||
| LRRCT | 716..772 | CDD:214507 | 13/57 (23%) | ||
| LRRNT | 796..830 | CDD:214470 | 11/33 (33%) | ||
| leucine-rich repeat | 812..829 | CDD:275380 | 5/16 (31%) | ||
| leucine-rich repeat | 833..854 | CDD:275380 | 7/20 (35%) | ||
| LRR_8 | 853..913 | CDD:290566 | 8/59 (14%) | ||
| leucine-rich repeat | 855..878 | CDD:275380 | 2/22 (9%) | ||
| LRR_4 | 878..918 | CDD:289563 | 7/39 (18%) | ||
| leucine-rich repeat | 879..902 | CDD:275380 | 4/22 (18%) | ||
| leucine-rich repeat | 903..926 | CDD:275380 | 6/40 (15%) | ||
| leucine-rich repeat | 927..953 | CDD:275380 | 6/28 (21%) | ||
| TIR | 1098..1235 | CDD:214587 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG4641 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D147327at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X221 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.820 | |||||