Protein Alignment SMYD5 and Smyd5

DIOPT Version :10

• Sequence 1: NP_006053.2
• Gene: SMYD5 / 10322
• HGNCID: 16258
• Length: 418
• Species: Homo sapiens
• Sequence 2: NP_650955.1
• Gene: Smyd5 / 42517
• FlyBaseID: FBgn0038869
• Length: 393
• Species: Drosophila melanogaster
• Alignment Length: 381
• Identity: 179/381 - (46%)
• Similarity: 244/381 - (64%)
• Gaps: 6/381 - (1%)

Human    32 KGKGLFATQLIRKGETIFVERPLVAAQFLWNALYRYRACDHCLRALEKAEENAQRLTGKPGQVLP 96
            ||:.:.||:...|.|.||.|.|.|:.||.||..|.|.|||||:|.||...||.:||...|...:|
  Fly    12 KGRAMIATKNFAKDEVIFEEEPFVSRQFSWNVAYGYAACDHCMRPLETVLENVRRLASDPKVEVP 76

Human    97 ----HPELCTVRKDLHQNCPHCQVMYCSAECRLAATEQYHQVLCPGPSQDDPLHPLNKLQEAWRS 157
                .|....|.:  ...||.|:|.|||.:|.:.|.::||:|.|.|....|..||:|.|.|.|:.
  Fly    77 LLQHDPTAQWVAQ--FTQCPRCKVRYCSEDCLMEAQKRYHRVACMGAFHSDDTHPINVLNETWKK 139

Human   158 IHYPPETASIMLMARMVATVKQAKDKDRWIRLFSQFCNKTANEEEEIVHKLLGDKFKGQLELLRR 222
            :||||||.||||:.|::|..:|:..|:.::.....|.:...|.|::|.||:||:.|:.|:|.|..
  Fly   140 MHYPPETGSIMLIVRLMALYQQSTKKEEFLEQLQSFQSLIVNREQKIYHKMLGENFEQQMEQLYL 204

Human   223 LFTEALYEEAVSQWFTPDGFRSLFALVGTNGQGIGTSSLSQWVHACDTLELKPQDREQLDAFIDQ 287
            .|..|...|..|.:.|||.|::|.|::|||.|||.||.|||||.....|.|...::||||..||.
  Fly   205 AFCNAFTGEEFSIFKTPDAFKTLMAILGTNSQGIATSVLSQWVAKVSDLPLTDSEKEQLDTVIDG 269

Human   288 LYKDIEAATGEFLNCEGSGLFVLQSCCNHSCVPNAETSFPENNFLLHVTALEDIKPGEEICISYL 352
            ||..:....|||||.|||||::|||..||||||||.::||.:|.::.:.||..|:.|||||||||
  Fly   270 LYAKVGEFAGEFLNNEGSGLYLLQSKINHSCVPNACSTFPYSNDIVVLKALAPIQQGEEICISYL 334

Human   353 DCCQRERSRHSRHKILRENYLFVCSCPKCLAEADEPNVTSEEEEEEEEEEEGEPED 408
            |.|..|||||||||:|||||:|:|.||||.|:|.:|:.|||::::::|.::.:.:|
  Fly   335 DECMLERSRHSRHKVLRENYVFICQCPKCRAQASDPDETSEDDDDDDEMDDYDDDD 390

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SMYD5	NP_006053.2	SET_SMYD5	22..384	CDD:380919	171/355 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	385..418		7/24 (29%)
Smyd5	NP_650955.1	SET_SMYD5	3..366	CDD:380919	171/355 (48%)
		zf-MYND	87..118	CDD:460312	13/32 (41%)