DRSC/TRiP Functional Genomics Resources

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Protein Alignment SMYD5 and SmydA-1

DIOPT Version :9

Sequence 1:NP_006053.2 Gene:SMYD5 / 10322 HGNCID:16258 Length:418 Species:Homo sapiens
Sequence 2:NP_610944.1 Gene:SmydA-1 / 36581 FlyBaseID:FBgn0033917 Length:513 Species:Drosophila melanogaster


Alignment Length:379 Identity:75/379 - (19%)
Similarity:111/379 - (29%) Gaps:157/379 - (41%)


- Green bases have known domain annotations that are detailed below.


Human    33 GKGLFATQLIRKGETIFVERPLVAAQFLWNALYRYRACDHCLRALEKAEENAQRLTGKPGQVLPH 97
            |:.|.||:.|:..|.:..|.|||...    |......|..||..:| ||:               
  Fly    52 GRHLVATRTIKPYEIVLKEAPLVRGP----AQISAPVCLGCLNGIE-AED--------------- 96

Human    98 PELCTVRKDLHQNCPHCQVMYCSAECRLAATEQYHQVLCPGPSQD-----------DPLHPLNKL 151
                      |..|..|....|..||:   :...|:..| |.::|           .| |||   
  Fly    97 ----------HIECEQCGWPLCGPECK---SLDEHKAEC-GLTKDRGQKVNVQEFGGP-HPL--- 143

Human   152 QEAWRSIHYPPETASIMLMARMVATVKQAKDKDRWIRLFSQFCNKTANEEEEIVHKLLGDKFKGQ 216
                    |...:....|:....:|.|.:|.:|                             ...
  Fly   144 --------YTCLSTVRCLLIGETSTEKASKFQD-----------------------------LES 171

Human   217 LELLRRLFTEALYEEAVSQWFTPDGFRSLFALVGTNGQGIGTSSLSQWVHACDTLELKPQDREQL 281
            ||..||                           |:|          ||          ..|...:
  Fly   172 LESTRR---------------------------GSN----------QW----------KADLVSI 189

Human   282 DAFIDQLYKDIEAATGEFLNCEGS----------------GLFVLQSCCNHSCVPNAETSFPENN 330
            ..||.:.:|..:....|.:...|:                .:|...|...:||:||...||.:|.
  Fly   190 GQFIPKFFKTQKFTEEEIMKAVGALQINGHEVPTTDPSHVAVFYTASFTENSCLPNLAKSFNKNG 254

Human   331 FLLHVTALEDIKPGEEICISYLDCC--QRERSRHSRHKILRENYLFVCSCPKCL 382
            ..: :.|..:||....:.|.|.|..  ..:|.||     |.:..||.|:|.:|:
  Fly   255 HCI-LWAPREIKKNAHLSICYSDAMWGTADRQRH-----LMQTKLFKCACERCV 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SMYD5NP_006053.2 SET <298..351 CDD:214614 15/68 (22%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 385..418
SmydA-1NP_610944.1 zf-MYND 4..40 CDD:280009
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG2084
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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