Protein Alignment NMUR1 and nmur1a

DIOPT Version :10

• Sequence 1: NP_006047.3
• Gene: NMUR1 / 10316
• HGNCID: 4518
• Length: 426
• Species: Homo sapiens
• Sequence 2: XP_021325138.1
• Gene: nmur1a / 557276
• ZFINID: ZDB-GENE-081104-220
• Length: 428
• Species: Danio rerio
• Alignment Length: 434
• Identity: 236/434 - (54%)
• Similarity: 302/434 - (69%)
• Gaps: 52/434 - (11%)

Human     2 TPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLT-----------DEALRLKYLGPQ 55
            ||.|:               ..:.||.|.|        ||||           ||.|. |||||:
Zfish    14 TPKCI---------------QDLLCNTSVA--------LNLTEMEIEDFCLDQDEYLE-KYLGPR 54

Human    56 QTELFMPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE 120
            ::.:|:|:|.||||||:||||||.|||:||.::|.||||||:||||||:|||||||:|:||||||
Zfish    55 RSPVFLPVCLTYLLIFLVGAVGNILTCIVIAKNKVMRTPTNFYLFSLAISDLLVLLLGMPLELYE 119

Human   121 MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAV 185
            ||.|||||||.|||||:|||||.||.||:|||||||||||:||:|||:|:.:|||.|.:|::.:|
Zfish   120 MWSNYPFLLGKGGCYFKTLLFETVCFASILNVTALSVERYIAVIHPLRAKYVVTRTHAKRLILSV 184

Human   186 WGLAMLCSLPNTSLHGIRQLHVP---CRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPMAIM 247
            |.:::||::|||.||||..|..|   ..|.:.|||.||||:||.:||:::|.|.||||.|||..:
Zfish   185 WSISVLCAIPNTILHGIFTLPPPKGKAAGVMLDSATCMLVKPRWMYNLIIQITTLLFFLLPMLTI 249

Human   248 SVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAP 312
            ||||||||::|:||::|.:.|||  .|:...|....|.||....|:|||||||||||:|||||||
Zfish   250 SVLYLLIGMQLKREKMLQVLEAK--ASSGLDSSSNVRSQQQKTRRQQVTKMLFVLVVMFGICWAP 312

Human   313 FHADRVMWSVVSQWTDGLHL----AFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALCL 373
            ||.||:|||.:.| .|..|:    .:::||||||:||||.||.|||||:|||:||||.|:|.:
Zfish   313 FHTDRLMWSFMDQ-KDSEHIEIFEVYEYVHVISGVFFYLSSAINPVLYNLMSTRFREMFKEVM-- 374

Human   374 GACCHRLR--PRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGND 415
              |.|:.|  ||..|.|::|:|..||:.||......| .:.|:|
Zfish   375 --CHHKWRPVPRKRSLSMTRVTVRSTVSDVPPCNGTV-TIEGDD 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NMUR1	NP_006047.3	7tmA_NMU-R1	61..367	CDD:320480	198/312 (63%)
		TM helix 1	61..88	CDD:320480	19/26 (73%)
		TM helix 2	95..121	CDD:320480	21/25 (84%)
		TM helix 3	134..164	CDD:320480	24/29 (83%)
		TM helix 4	176..198	CDD:320480	8/21 (38%)
		TM helix 5	228..257	CDD:320480	19/28 (68%)
		TM helix 6	290..320	CDD:320480	23/29 (79%)
		TM helix 7	335..360	CDD:320480	18/24 (75%)
nmur1a	XP_021325138.1	7tmA_NMU-R1	60..370	CDD:320480	198/312 (63%)
		TM helix 1	60..87	CDD:320480	19/26 (73%)
		TM helix 2	94..120	CDD:320480	21/25 (84%)
		TM helix 3	133..163	CDD:320480	24/29 (83%)
		TM helix 4	175..197	CDD:320480	8/21 (38%)
		TM helix 5	230..259	CDD:320480	19/28 (68%)
		TM helix 6	290..320	CDD:320480	23/29 (79%)
		TM helix 7	338..363	CDD:320480	18/24 (75%)