Protein Alignment NMUR1 and Nmur1

DIOPT Version :10

• Sequence 1: NP_006047.3
• Gene: NMUR1 / 10316
• HGNCID: 4518
• Length: 426
• Species: Homo sapiens
• Sequence 2: NP_001306156.1
• Gene: Nmur1 / 14767
• MGIID: 1341898
• Length: 428
• Species: Mus musculus
• Alignment Length: 428
• Identity: 310/428 - (72%)
• Similarity: 347/428 - (81%)
• Gaps: 2/428 - (0%)

Human     1 MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELFMPICA 65
            |||.|||||:.||.|.|..:|:|:.||.|..:..:.||||||||||||||||||||.:.|:|||.
Mouse     1 MTPPCLNCSIFPGALSPNASRSPLVCNISEFKWPYQPEDLNLTDEALRLKYLGPQQMKQFVPICV 65

Human    66 TYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYEMWHNYPFLLG 130
            |||||||||.:||||||.||||:|.||||||:|||||||||:||||||||||||||..||||.||
Mouse    66 TYLLIFVVGTLGNGLTCTVILRNKTMRTPTNFYLFSLAVSDMLVLLVGLPLELYEMQQNYPFQLG 130

Human   131 VGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRRVLGAVWGLAMLCSLP 195
            ...||||.||.|.|||||||||||||||||||||.||||:|::|||||||::||:|.||.|.|||
Mouse   131 ASACYFRILLLETVCLASVLNVTALSVERYVAVVRPLQAKSVMTRAHVRRMVGAIWVLATLFSLP 195

Human   196 NTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFFCLPMAIMSVLYLLIGLRLRR 260
            ||||||:.||.|||||||||||:|.||.|...|.:||.|||||||||||..:|||||||||||||
Mouse   196 NTSLHGLSQLTVPCRGPVPDSAICSLVGPMDFYKLVVLTTALLFFCLPMVTISVLYLLIGLRLRR 260

Human   261 ERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLFVLVVVFGICWAPFHADRVMWSVV-S 324
            ||:||..|.|||.:||.:.....|:|..||||||||||||.||||||||||||||||:|||:| .
Mouse   261 ERMLLQVEVKGRKTAATQETSHRRIQLQDRGRRQVTKMLFALVVVFGICWAPFHADRIMWSLVYG 325

Human   325 QWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMSSRFRETFQEALCLGA-CCHRLRPRHSSHS 388
            ..|:|||||:|.||:.||||||||||||||||||||:||||||.:||.||. ||||.:|.|.||:
Mouse   326 HSTEGLHLAYQCVHIASGIFFYLGSAANPVLYSLMSTRFRETFLQALGLGTQCCHRRQPYHGSHN 390

Human   389 LSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQQETDPS 426
            ..|:||||||||||...|...|||.|:.|..|||||||
Mouse   391 HIRLTTGSTLCDVGHRNSRDEPLAVNEDPGCQQETDPS 428

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NMUR1	NP_006047.3	7tmA_NMU-R1	61..367	CDD:320480	234/306 (76%)
		TM helix 1	61..88	CDD:320480	21/26 (81%)
		TM helix 2	95..121	CDD:320480	23/25 (92%)
		TM helix 3	134..164	CDD:320480	26/29 (90%)
		TM helix 4	176..198	CDD:320480	15/21 (71%)
		TM helix 5	228..257	CDD:320480	22/28 (79%)
		TM helix 6	290..320	CDD:320480	27/29 (93%)
		TM helix 7	335..360	CDD:320480	21/24 (88%)
Nmur1	NP_001306156.1	7tmA_NMU-R1	61..368	CDD:320480	234/306 (76%)
		TM helix 1	61..88	CDD:320480	21/26 (81%)
		TM helix 2	95..121	CDD:320480	23/25 (92%)
		TM helix 3	134..164	CDD:320480	26/29 (90%)
		TM helix 4	176..198	CDD:320480	15/21 (71%)
		TM helix 5	228..257	CDD:320480	22/28 (79%)
		TM helix 6	290..320	CDD:320480	27/29 (93%)
		TM helix 7	336..361	CDD:320480	21/24 (88%)