Protein Alignment VPS26C and CG4074

DIOPT Version :10

• Sequence 1: NP_006043.1
• Gene: VPS26C / 10311
• HGNCID: 3044
• Length: 297
• Species: Homo sapiens
• Sequence 2: NP_649249.2
• Gene: CG4074 / 40290
• FlyBaseID: FBgn0037017
• Length: 316
• Species: Drosophila melanogaster
• Alignment Length: 303
• Identity: 151/303 - (49%)
• Similarity: 212/303 - (69%)
• Gaps: 19/303 - (6%)

Human     6 DIKIKRANKVYHAGEVLSGVVVISSKDSVQHQGVSLTMEGTVNLQLSAKSVGVFEAFYNSVKPIQ 70
            |||:||.|||||..::|.|.|........:|:|:.|.:||.||||||||:||:|:|||||||||.
  Fly     7 DIKLKRENKVYHENDMLLGCVQFQCAQETKHEGIILYLEGIVNLQLSAKTVGLFDAFYNSVKPIN 71

Human    71 IINSTIEMVKPGKFPSGKTEIPFEFPLHLKGN-KVLYETYHGVFVNIQYTLRCDMKRSLLAKDLT 134
            ::.:::|:..|||..:|::|..||.||..|.. ::|||||||||:|:.|.|.|.:||:.|.|..|
  Fly    72 LLQNSLELSAPGKLSAGRSEFHFELPLVCKKEPRILYETYHGVFINVNYQLTCTVKRNFLGKATT 136

Human   135 KTCEFIVHSAPQKGKFTPSP--------VDFTITPETLQ---NVKERALLPKFLLRGHLNSTNCV 188
            |..:|.|       ::.|.|        |.|:::|::||   :.|||..:|:||:.|.|:.:...
  Fly   137 KIQQFCV-------QYKPVPLSEDSKKVVPFSLSPDSLQKNASAKERLSMPRFLITGRLDRSEFC 194

Human   189 ITQPLTGELVVESSEAAIRSVELQLVRVETCGCAEGYARDATEIQNIQIADGDVCRGLSVPIYMV 253
            :|.|:||.:.|:.:||||:|:|:||||||||||.|||::||||||.||||||:|...|.:||:||
  Fly   195 VTTPITGSITVQHTEAAIKSIEMQLVRVETCGCDEGYSKDATEIQTIQIADGNVLPKLELPIHMV 259

Human   254 FPRLFTCPTLETTNFKVEFEVNIVVLLHPDHLITENFPLKLCR 296
            .|||||||||.|.|||:|||:|::|:...|:.::|||.:.|.|
  Fly   260 LPRLFTCPTLLTKNFKIEFELNLIVVFKEDYTVSENFKIVLKR 302

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
VPS26C	NP_006043.1	Arrestin_N	1..283	CDD:451447	145/288 (50%)
CG4074	NP_649249.2	Arrestin_N	6..289	CDD:451447	145/288 (50%)